Energy balance and colorectal cancer risk: A role for cancer cell metabolism?

Josien Christina Anna Jenniskens

Research output: ThesisDoctoral ThesisInternal

384 Downloads (Pure)

Abstract

In this thesis, it was investigated whether cancer cell metabolism might play a role in the association between energy balance and colorectal cancer risk. To investigate this, colorectal cancer cases were divided into subgroups that give an indication of the metabolism that is used by the cancer cells. Associations between energy balance-related factors (overweight, physical activity, height, and energy restriction) and these subgroups of colorectal cancer based on cancer cell metabolism were investigated. The results gave an indication on whether or not cancer cell metabolism might play a role in the associations between energy balance-related factors and colorectal cancer risk.
Original languageEnglish
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • van den Brandt, Piet, Supervisor
  • Grabsch, Heike, Supervisor
  • Simons, Colinda, Co-Supervisor
Award date4 Nov 2022
Place of PublicationMaastricht
Publisher
Print ISBNs9789464585643
DOIs
Publication statusPublished - 2022

Keywords

  • energy balance
  • colorectal cancer
  • etiology
  • metabolism

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