Endothelial progenitor cells--potential new avenues to improve neoangiogenesis and reendothelialization

Andrzej Piatkowski, G. Grieb, D. Simons, J. Bernhagen, Rene van der Hulst

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

    Abstract

    The term endothelial progenitor cell (EPC) was established more than 10 years ago and is used to refer to a group of circulating cells that display endothelial lineage qualities and are able to home to areas of ischemia or vascular injury and to facilitate the repair of damaged blood vessels or develop new vessels as needed. This chapter reviews the current lineage relationships among all the cells called EPC and will clear the terminology used in EPC research. Furthermore, an overview of the clinical and in vitro research, as well as cytokine and drug interactions and potential EPC applications, is given.
    Original languageEnglish
    Title of host publicationInternational Review of Cell and Molecular Biology
    EditorsKwang W. Jeon
    Pages43-81
    Number of pages39
    DOIs
    Publication statusPublished - 1 Jan 2013

    Publication series

    SeriesInternational Review of Cell and Molecular Biology
    Volume306
    ISSN1937-6448

    Keywords

    • ACUTE MYOCARDIAL-INFARCTION
    • COLONY-STIMULATING FACTOR
    • CORONARY-ARTERY-DISEASE
    • NITRIC-OXIDE SYNTHASE
    • HEMATOPOIETIC STEM-CELLS
    • LEFT-VENTRICULAR FUNCTION
    • ACUTE ISCHEMIC-STROKE
    • BONE-MARROW
    • IN-VITRO
    • RHEUMATOID-ARTHRITIS

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