Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects and Endothelial-Mesenchymal Transition

Colin E. Murdoch, Sanjay Chaubey, Lingfang Zeng, Bin Yu, Aleksander Ivetic, Simon J. Walker, Davy Vanhoutte, Stephane Heymans, David J. Grieve, Alison C. Cave, Alison C. Brewer, Min Zhang, Ajay M. Shah

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2734-2741
JournalJournal of the American College of Cardiology
Volume63
Issue number24
DOIs
Publication statusPublished - 24 Jun 2014

Keywords

  • angiotensin II
  • diastolic dysfunction
  • endothelial-mesenchymal transition
  • endothelium
  • NADPH (nicotinamide adenine dinucleotide phosphate) oxidase

Cite this

Murdoch, C. E., Chaubey, S., Zeng, L., Yu, B., Ivetic, A., Walker, S. J., Vanhoutte, D., Heymans, S., Grieve, D. J., Cave, A. C., Brewer, A. C., Zhang, M., & Shah, A. M. (2014). Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects and Endothelial-Mesenchymal Transition. Journal of the American College of Cardiology, 63(24), 2734-2741. https://doi.org/10.1016/j.jacc.2014.02.572