Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury

Terezinha Souza*, Panuwat Trairatphisan, Janet Pinero, Laura Furlong, Julio Saez-Rodriguez, Jos Kleinjans, Danyel Jennen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number527
Number of pages12
JournalFrontiers in Genetics
Volume9
DOIs
Publication statusPublished - 20 Nov 2018

Keywords

  • annotation
  • DILI
  • gene ontology
  • text mining
  • network biology
  • translational bioinformatics
  • LONG NONCODING RNAS
  • EXPRESSION SIGNATURES
  • TRANSCRIPTION FACTORS
  • DNA-DAMAGE
  • IN-VITRO
  • NETWORK
  • TARGETS
  • CANCER
  • TOXICOGENOMICS
  • TOXICOLOGY

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