Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras

Inga Nachreiner, Ahmad Fawzi Hussain*, Ulrich Wullner, Nikolaus Machuy, Thomas F. Meyer, Rainer Fischer, Stefan Gattenloehner, Ivo Meinhold-Heerlein, Stefan Barth, Mehmet Kemal Tur

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2401-2412
Number of pages12
JournalExperimental and Therapeutic Medicine
Volume18
Issue number4
DOIs
Publication statusPublished - Oct 2019

Keywords

  • aptamer
  • RNA interference
  • breast cancer
  • aptamer-siRNA chimera
  • targeted cancer therapy
  • human epidermal growth factor receptor-3
  • RNA INTERFERENCE
  • KINASE 1
  • GROWTH
  • APOPTOSIS
  • DELIVERY
  • HER3
  • GENE
  • INHIBITION
  • EXPRESSION
  • RECEPTOR

Cite this

Nachreiner, I., Hussain, A. F., Wullner, U., Machuy, N., Meyer, T. F., Fischer, R., Gattenloehner, S., Meinhold-Heerlein, I., Barth, S., & Tur, M. K. (2019). Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras. Experimental and Therapeutic Medicine, 18(4), 2401-2412. https://doi.org/10.3892/etm.2019.7753