Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

Julian I. Borissoff; Ivo A. Joosen; Mathijs O. Versteylen; Alexander Brill; Tobias A. Fuchs; Alexander S. Savchenko; Maureen Gallant; Kimberly Martinod; Hugo ten Cate; Leonard Hofstra; Harry J. Crijns; Denisa D. Wagner; Bas L. J. H. Kietselaer

doi:10.1161/ATVBAHA.113.301627

Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

Julian I. Borissoff, Ivo A. Joosen, Mathijs O. Versteylen, Alexander Brill, Tobias A. Fuchs, Alexander S. Savchenko, Maureen Gallant, Kimberly Martinod, Hugo ten Cate, Leonard Hofstra, Harry J. Crijns, Denisa D. Wagner, Bas L. J. H. Kietselaer

Research output: Contribution to journal › Article › Academic › peer-review

82 Citations (Scopus)

Original language	English
Pages (from-to)	2032-2040
Journal	Arteriosclerosis Thrombosis and Vascular Biology
Volume	33
Issue number	8
DOIs	https://doi.org/10.1161/ATVBAHA.113.301627
Publication status	Published - Aug 2013

Keywords

atherosclerosis
coagulation
blood
chromatin
DNA
neutrophils
nucleosomes
thrombin
thrombophilia

Access to Document

10.1161/ATVBAHA.113.301627

Cite this

Borissoff, J. I., Joosen, I. A., Versteylen, M. O., Brill, A., Fuchs, T. A., Savchenko, A. S., Gallant, M., Martinod, K., ten Cate, H., Hofstra, L., Crijns, H. J., Wagner, D. D., & Kietselaer, B. L. J. H. (2013). Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State. Arteriosclerosis Thrombosis and Vascular Biology, 33(8), 2032-2040. https://doi.org/10.1161/ATVBAHA.113.301627

Borissoff, Julian I. ; Joosen, Ivo A. ; Versteylen, Mathijs O. ; Brill, Alexander ; Fuchs, Tobias A. ; Savchenko, Alexander S. ; Gallant, Maureen ; Martinod, Kimberly ; ten Cate, Hugo ; Hofstra, Leonard ; Crijns, Harry J. ; Wagner, Denisa D. ; Kietselaer, Bas L. J. H. / Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State. In: Arteriosclerosis Thrombosis and Vascular Biology. 2013 ; Vol. 33, No. 8. pp. 2032-2040.

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title = "Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State",

keywords = "atherosclerosis, coagulation, blood, chromatin, DNA, neutrophils, nucleosomes, thrombin, thrombophilia",

author = "Borissoff, {Julian I.} and Joosen, {Ivo A.} and Versteylen, {Mathijs O.} and Alexander Brill and Fuchs, {Tobias A.} and Savchenko, {Alexander S.} and Maureen Gallant and Kimberly Martinod and {ten Cate}, Hugo and Leonard Hofstra and Crijns, {Harry J.} and Wagner, {Denisa D.} and Kietselaer, {Bas L. J. H.}",

year = "2013",

month = aug,

doi = "10.1161/ATVBAHA.113.301627",

language = "English",

volume = "33",

pages = "2032--2040",

journal = "Arteriosclerosis Thrombosis and Vascular Biology",

issn = "1079-5642",

publisher = "LIPPINCOTT WILLIAMS & WILKINS",

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Borissoff, JI, Joosen, IA, Versteylen, MO, Brill, A, Fuchs, TA, Savchenko, AS, Gallant, M, Martinod, K, ten Cate, H, Hofstra, L, Crijns, HJ, Wagner, DD & Kietselaer, BLJH 2013, 'Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State', Arteriosclerosis Thrombosis and Vascular Biology, vol. 33, no. 8, pp. 2032-2040. https://doi.org/10.1161/ATVBAHA.113.301627

Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State. / Borissoff, Julian I.; Joosen, Ivo A.; Versteylen, Mathijs O.; Brill, Alexander; Fuchs, Tobias A.; Savchenko, Alexander S.; Gallant, Maureen; Martinod, Kimberly; ten Cate, Hugo; Hofstra, Leonard; Crijns, Harry J.; Wagner, Denisa D.; Kietselaer, Bas L. J. H.

In: Arteriosclerosis Thrombosis and Vascular Biology, Vol. 33, No. 8, 08.2013, p. 2032-2040.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

AU - Borissoff, Julian I.

AU - Joosen, Ivo A.

AU - Versteylen, Mathijs O.

AU - Brill, Alexander

AU - Fuchs, Tobias A.

AU - Savchenko, Alexander S.

AU - Gallant, Maureen

AU - Martinod, Kimberly

AU - ten Cate, Hugo

AU - Hofstra, Leonard

AU - Crijns, Harry J.

AU - Wagner, Denisa D.

AU - Kietselaer, Bas L. J. H.

PY - 2013/8

Y1 - 2013/8

KW - atherosclerosis

KW - coagulation

KW - blood

KW - chromatin

KW - DNA

KW - neutrophils

KW - nucleosomes

KW - thrombin

KW - thrombophilia

U2 - 10.1161/ATVBAHA.113.301627

DO - 10.1161/ATVBAHA.113.301627

M3 - Article

VL - 33

SP - 2032

EP - 2040

JO - Arteriosclerosis Thrombosis and Vascular Biology

JF - Arteriosclerosis Thrombosis and Vascular Biology

SN - 1079-5642

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ER -