Electrospinning for drug delivery applications: A review

Andrea Luraghi, Francesco Peri, Lorenzo Moroni*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

102 Citations (Web of Science)

Abstract

Drug delivery devices are promising tools in the pharmaceutical field, as they are able to maximize the therapeutic effects of the delivered drug while minimizing the undesired side effects. In the past years, electrospun nanofibers attracted rising attention due to their unique features, like biocompatibility and broad flexibility. Incorporation of active principles in nanofibrous meshes proved to be an efficient method for in situ delivery of a wide range of drugs, expanding the possibility and applicability of those devices. In this review, the principle of electrospinning and different fields of applications are treated to give an overview of the recent literature, underlining the easy tuning and endless combination of this technique, that in the future could be the new frontier of personalized medicine.

Original languageEnglish
Pages (from-to)463-484
Number of pages22
JournalJournal of Controlled Release
Volume334
DOIs
Publication statusPublished - 10 Jun 2021

Keywords

  • Electrospinning
  • Drug delivery
  • Nanofibers
  • Tissue engineering
  • Controlled release
  • MULTIDRUG-RESISTANCE
  • WOUND CARE
  • NANOFIBERS
  • RELEASE
  • FIBERS
  • SYSTEMS
  • CANCER
  • FABRICATION
  • MORPHOLOGY
  • SENSORS

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