Electrochemical Sensors for Antibiotic Detection: A Focused Review with a Brief Overview of Commercial Technologies

Research output: Contribution to journal(Systematic) Review article peer-review

Abstract

Antimicrobial resistance (AMR) poses a significant threat to global health, powered by pathogens that become increasingly proficient at withstanding antibiotic treatments. This review introduces the factors contributing to antimicrobial resistance (AMR), highlighting the presence of antibiotics in different environmental and biological matrices as a significant contributor to the resistance. It emphasizes the urgent need for robust and effective detection methods to identify these substances and mitigate their impact on AMR. Traditional techniques, such as liquid chromatography-mass spectrometry (LC-MS) and immunoassays, are discussed alongside their limitations. The review underscores the emerging role of biosensors as promising alternatives for antibiotic detection, with a particular focus on electrochemical biosensors. Therefore, the manuscript extensively explores the principles and various types of electrochemical biosensors, elucidating their advantages, including high sensitivity, rapid response, and potential for point-of-care applications. Moreover, the manuscript investigates recent advances in materials used to fabricate electrochemical platforms for antibiotic detection, such as aptamers and molecularly imprinted polymers, highlighting their role in enhancing sensor performance and selectivity. This review culminates with an evaluation and summary of commercially available and spin-off sensors for antibiotic detection, emphasizing their versatility and portability. By explaining the landscape, role, and future outlook of electrochemical biosensors in antibiotic detection, this review provides insights into the ongoing efforts to combat the escalating threat of AMR effectively.
Original languageEnglish
Article number5576
Number of pages27
JournalSensors
Volume24
Issue number17
DOIs
Publication statusPublished - 1 Sept 2024

Keywords

  • antibiotics
  • antibiotic resistance
  • antimicrobial resistance
  • analytical techniques
  • biosensors
  • optical biosensors
  • electrochemical biosensors
  • antibiotic residue
  • BIOSENSORS
  • NANOCOMPOSITE
  • RESISTANCE
  • RESIDUES
  • SULFAMETHOXAZOLE
  • NANOPARTICLES
  • APTASENSOR
  • ANTIBODIES

Fingerprint

Dive into the research topics of 'Electrochemical Sensors for Antibiotic Detection: A Focused Review with a Brief Overview of Commercial Technologies'. Together they form a unique fingerprint.

Cite this