Efficacy of gene therapy-delivered cytosine deaminase is determined by enzymatic activity but not expression

L. Dubois, T. Dresselaers, W. Landuyt, K. Paesmans, A. Mengesha, B. G. Wouters, P. Van Hecke, J. Theys*, P. Lambin

*Corresponding author for this work

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science

Immunology and Microbiology