Keyphrases
Randomized Placebo-controlled Trial
100%
Type 2 Diabetes Mellitus (T2DM)
100%
Inflammatory Activity
100%
Short-term Treatment
100%
Metformin
100%
Endothelial Function
100%
Functions Activities
100%
Placebo
40%
Low-grade Inflammation
30%
Insulin
30%
Glycemic Control
30%
Metabolic Effects
30%
Metformin Treatment
30%
Pregnant Women
20%
Hyperinsulinemia
20%
Netherlands
10%
Patient-completed
10%
Blood Samples
10%
Diabetes
10%
Informed Consent
10%
Diabetes Diagnosis
10%
Outpatient Clinic
10%
C-reactive Protein
10%
Von Willebrand Factor
10%
Inflammation Markers
10%
Insulin Therapy
10%
Treatment Duration
10%
Congestive Heart Failure
10%
Type 2 Diabetic Patients
10%
Urinary Albumin Excretion
10%
New York Heart Association Class
10%
Cockroft-Gault
10%
Soluble Intercellular Adhesion molecule-1 (sICAM-1)
10%
Plasminogen Activator inhibitor-1 (PAI-1)
10%
Interim Analysis
10%
Tissue Plasminogen Activator (t-PA)
10%
Insulin Dose
10%
Cardiovascular Effects
10%
Non-academic Hospital
10%
Glucose-lowering Drugs
10%
Soluble Vascular Cell Adhesion molecule-1
10%
Soluble E-selectin
10%
Oral Agents
10%
Psychiatric Disease
10%
Ketoacidosis
10%
Double-blind Trial
10%
Medical Illness
10%
Blood Glucose Reduction
10%
Control Body
10%
Plasma Cholinesterase
10%
Estimated Creatinine Clearance
10%
INIS
patients
100%
diabetes mellitus
100%
inflammation
100%
insulin
62%
control
37%
women
25%
blood
25%
molecules
25%
plasma
25%
adhesion
25%
plasminogen
25%
diseases
12%
data
12%
doses
12%
glucose
12%
values
12%
therapy
12%
tissues
12%
mortality
12%
comparative evaluations
12%
netherlands
12%
hospitals
12%
morbidity
12%
units
12%
design
12%
weight
12%
new york
12%
clearance
12%
creatinine
12%
heart failure
12%
fasting
12%
excretion
12%
c-reactive protein
12%
albumins
12%
cholinesterase
12%
Medicine and Dentistry
Placebo
100%
Maturity Onset Diabetes of the Young
100%
Endothelial Function
100%
Glycon
100%
Short Course Therapy
100%
Glycemic Control
23%
Diabetes
15%
Hyperinsulinemia
15%
Informed Consent
7%
Urinary System
7%
C Reactive Protein
7%
Body Weight
7%
Cardiovascular Effect
7%
Von Willebrand Factor
7%
Patient with Type 2 Diabetes
7%
Blood Glucose
7%
Tissue Plasminogen Activator
7%
Outpatient
7%
Creatinine Clearance
7%
Endothelial Leukocyte Adhesion Molecule 1
7%
Physical Examination
7%
Intercellular Adhesion Molecule 1
7%
Vascular Cell Adhesion Molecule 1
7%
Insulin Treatment
7%
New York Heart Association Class
7%
Patient with Congestive Heart Failure
7%
Interim Analysis
7%
Cholinesterase
7%
Ketoacidosis
7%
Plasminogen Activator Inhibitor-1
7%
Pharmacology, Toxicology and Pharmaceutical Science
Placebo
100%
Metformin
100%
Non Insulin Dependent Diabetes Mellitus
100%
Inflammation
30%
Hyperinsulinemia
15%
C Reactive Protein
7%
Von Willebrand Factor
7%
Plasminogen Activator Inhibitor 1
7%
Tissue Plasminogen Activator
7%
Creatinine
7%
Vascular Cell Adhesion Molecule 1
7%
E-Selectin
7%
Intercellular Adhesion Molecule 1
7%
Congestive Heart Failure
7%
Cholinesterase
7%
Ketoacidosis
7%