Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice

S. den Hoedt, S.M. Crivelli, F.P.J. Leijten, M. Losen, J.A.A. Stevens, M. Mane-Damas, H.E. De Vries, J. Walter, M. Mirzaian, E.J.G. Sijbrands, J.M.F.G. Aerts, A.J.M. Verhoeven, P. Martinez-Martinez*, M.T. Mulder*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number765252
Number of pages11
JournalFrontiers in Aging Neuroscience
Volume13
DOIs
Publication statusPublished - 27 Oct 2021

Keywords

  • ceramide
  • S1P
  • apolipoprotein E4
  • Alzheimer's disease
  • aging
  • sex differences
  • TRANSGENIC MOUSE MODEL
  • SPHINGOLIPID METABOLISM
  • SPHINGOSINE 1-PHOSPHATE
  • CHOLESTEROL-METABOLISM
  • CEREBROSPINAL-FLUID
  • DEPENDENT CHANGES
  • PLASMA CERAMIDES
  • OXIDATIVE STRESS
  • TYPE-4 ALLELE
  • RISK

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