TY - JOUR
T1 - Effects of prehabilitation and rehabilitation including a home-based component on physical fitness, adherence, treatment tolerance, and recovery in patients with non-small cell lung cancer
T2 - A systematic review
AU - Driessen, Elisabeth J.
AU - Peeters, Marieke E.
AU - Bongers, Bart C.
AU - Maas, Huub A.
AU - Bootsma, Gerbern P.
AU - van Meeteren, Nico L.
AU - Janssen-Heijnen, Maryska L.
PY - 2017/6
Y1 - 2017/6
N2 - This systematic review aimed to examine physical fitness, adherence, treatment tolerance, and recovery for (p)rehabilitation including a home-based component for patients with non-small cell lung cancer (NSCLC). PRISMA and Cochrane guidelines were followed. Studies describing (home-based) prehabilitation or rehabilitation in patients with NSCLC were included from four databases (January 2000-April 2016, N= 11). Nine of ten rehabilitation studies and one prehabilitation study (437 NSCLC patients, mean age 59-72 years) showed significantly or clinically relevant improved physical fitness. Three (27%) assessed home-based training and eight (73%) combined training at home, inhospital (intramural) and/or at the physiotherapy practice/department (extramural). Six (55%) applied supervision of home-based components, and four (36%) a personalized training program. Adherence varied strongly (9-125% for exercises, 50-100% for patients). Treatment tolerance and recovery were heterogeneously reported. Although promising results of (p)rehabilitation for improving physical fitness were found (especially in case of supervision and personalization), adequately powered studies for home-based (p)rehabilitation are needed. (C) 2017 Elsevier B.V. All rights reserved.
AB - This systematic review aimed to examine physical fitness, adherence, treatment tolerance, and recovery for (p)rehabilitation including a home-based component for patients with non-small cell lung cancer (NSCLC). PRISMA and Cochrane guidelines were followed. Studies describing (home-based) prehabilitation or rehabilitation in patients with NSCLC were included from four databases (January 2000-April 2016, N= 11). Nine of ten rehabilitation studies and one prehabilitation study (437 NSCLC patients, mean age 59-72 years) showed significantly or clinically relevant improved physical fitness. Three (27%) assessed home-based training and eight (73%) combined training at home, inhospital (intramural) and/or at the physiotherapy practice/department (extramural). Six (55%) applied supervision of home-based components, and four (36%) a personalized training program. Adherence varied strongly (9-125% for exercises, 50-100% for patients). Treatment tolerance and recovery were heterogeneously reported. Although promising results of (p)rehabilitation for improving physical fitness were found (especially in case of supervision and personalization), adequately powered studies for home-based (p)rehabilitation are needed. (C) 2017 Elsevier B.V. All rights reserved.
KW - Non-small cell lung cancer
KW - Prehabilitation
KW - Rehabilitation
KW - Physical therapy
KW - Compliance
KW - Tolerance
KW - Home
KW - RANDOMIZED CONTROLLED-TRIAL
KW - QUALITY-OF-LIFE
KW - CLINICALLY IMPORTANT IMPROVEMENT
KW - MINIMAL IMPORTANT DIFFERENCE
KW - ESMO CONSENSUS CONFERENCE
KW - FRAIL OLDER-ADULTS
KW - SHUTTLE WALK TEST
KW - EXERCISE INTERVENTION
KW - PULMONARY REHABILITATION
KW - FUNCTIONAL STATUS
U2 - 10.1016/j.critrevonc.2017.03.031
DO - 10.1016/j.critrevonc.2017.03.031
M3 - (Systematic) Review article
C2 - 28477748
SN - 1040-8428
VL - 114
SP - 63
EP - 76
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
ER -