Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers

Keyphrases

• Smokers 100%
• Oral Administration 100%
• Biomarker Studies 100%
• N-acetylcysteine 100%
• Multi-biomarker 100%
• DNA Adducts 40%
• Antioxidant Scavenging Capacity 30%
• Bronchoalveolar Lavage Fluid 20%
• Inhibitory Effect 20%
• Floor of Mouth 20%
• Biological Response 20%
• Biologically Effective Dose 20%
• Internal Exposure 20%
• Response Marker 20%
• Hemoglobin Adducts 20%
• Lipophilic 20%
• Placebo 10%
• Randomized Double-blind 10%
• Placebo-controlled 10%
• Protective Effect 10%
• Cotinine 10%
• Stimulatory Effect 10%
• Carcinogenicity 10%
• Protective Mechanism 10%
• Cancer-related 10%
• Tobacco Smoke 10%
• Oral Tablets 10%
• 8-oxoguanine 10%
• Micronucleus Frequency 10%
• Micronucleus 10%
• Polycyclic Aromatic Hydrocarbons 10%
• Soft Palate 10%
• Bronchoalveolar Lavage Cells 10%
• Mutagenicity 10%
• Plasma Antioxidants 10%
• 4-aminobiphenyl 10%
• Trolox 10%
• Chemoprevention Trial 10%
• 5′-nucleotides 10%
• Peripheral Blood Lymphocytes 10%
• Buccal mucosa Cells 10%
• Placebo Groups 10%

INIS

• biological markers 100%
• oral administration 100%
• cysteine 100%
• dna adducts 40%
• capacity 30%
• lavage 30%
• antioxidants 30%
• adducts 30%
• scavenging 30%
• doses 20%
• cancer 20%
• nucleotides 20%
• floors 20%
• fluids 20%
• plasma 20%
• hemoglobin 20%
• mouth 20%
• effective doses 20%
• humans 10%
• comparative evaluations 10%
• blood 10%
• urine 10%
• mucosa 10%
• organs 10%
• lymphocytes 10%
• tobacco smokes 10%
• polycyclic aromatic hydrocarbons 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Cysteine 100%
• Acetic Acid Derivative 100%
• Biomarker Study 100%
• Placebo 30%
• Antioxidant 30%
• Malignant Neoplasm 20%
• Polycyclic Aromatic Hydrocarbon 10%
• Biological Marker 10%
• Carcinogenicity 10%
• Cotinine 10%
• 4-Aminobiphenyl 10%
• Trolox C 10%
• Mutagenicity 10%
• 8 Hydroxydeoxyguanosine 10%
• Tablet 10%