Effectiveness of Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease With Different Degrees of Static Lung Hyperinflation

Michiel J. Vanfleteren*, Maud Koopman, Martijn A. Spruit, Herman-Jan Pennings, Frank Smeenk, Willem Pieters, Jan J. van den Bergh, Arent-Jan Michels, Emiel F. Wouters, Miriam T. Groenen, Frits M. Franssen, Lowie E. Vanfleteren

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Objective: To evaluate the effect of pulmonary rehabilitation (PR) on exercise performance and quality of life in patients with chronic obstructive pulmonary disease (COPD) with different degrees of static lung hyperinflation (LH).

Design: Retrospective cohort study.

Setting: PR network.

Participants: A cohort of 1981 patients with COPD (55% men; age: 66.8 +/- 9.3y; forced expiratory volume in the first second%: 50.7 +/- 19.5; residual volume [RV]%: 163.0 +/- 49.7).

Intervention: An interdisciplinary PR program for patients with COPD consisting of 40 sessions.

Main Outcome Measures: Participants were stratified into 5 quintiles according to baseline RV and were evaluated on the basis of pre- and post - PR 6-minute walk distance (6MWD), constant work rate test (CWRT), and Saint George's Respiratory Questionnaire (SGRQ), among other clinical parameters.

Results: With increasing RV quintile, patients were younger, more frequently women, had lower forced expiratory volume in the first second%, lower body mass index and fat-free mass index, shorter 6MWD, shorter CWRT, and worse SGRQ scores (P

Conclusions: LH in COPD is related to younger age, female sex, lower body weight, worse exercise capacity and health status, but did not prevent patients from benefitting from PR. LH, however, influences walking and cycling response after PR differently. (C) 2018 by the American Congress of Rehabilitation Medicine

Original languageEnglish
Pages (from-to)2279-2286
Number of pages8
JournalArchives of Physical Medicine and Rehabilitation
Volume99
Issue number11
DOIs
Publication statusPublished - Nov 2018

Keywords

  • COPD
  • Rehabilitation
  • FIELD WALKING TESTS
  • MUSCLE DYSFUNCTION
  • EXERCISE PERFORMANCE
  • NATIONAL EMPHYSEMA
  • HEALTH-STATUS
  • MECHANISMS
  • CAPACITY
  • IMPACT

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