TY - JOUR
T1 - Effectiveness of Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease With Different Degrees of Static Lung Hyperinflation
AU - Vanfleteren, Michiel J.
AU - Koopman, Maud
AU - Spruit, Martijn A.
AU - Pennings, Herman-Jan
AU - Smeenk, Frank
AU - Pieters, Willem
AU - van den Bergh, Jan J.
AU - Michels, Arent-Jan
AU - Wouters, Emiel F.
AU - Groenen, Miriam T.
AU - Franssen, Frits M.
AU - Vanfleteren, Lowie E.
PY - 2018/11
Y1 - 2018/11
N2 - Objective: To evaluate the effect of pulmonary rehabilitation (PR) on exercise performance and quality of life in patients with chronic obstructive pulmonary disease (COPD) with different degrees of static lung hyperinflation (LH).Design: Retrospective cohort study.Setting: PR network.Participants: A cohort of 1981 patients with COPD (55% men; age: 66.8 +/- 9.3y; forced expiratory volume in the first second%: 50.7 +/- 19.5; residual volume [RV]%: 163.0 +/- 49.7).Intervention: An interdisciplinary PR program for patients with COPD consisting of 40 sessions.Main Outcome Measures: Participants were stratified into 5 quintiles according to baseline RV and were evaluated on the basis of pre- and post - PR 6-minute walk distance (6MWD), constant work rate test (CWRT), and Saint George's Respiratory Questionnaire (SGRQ), among other clinical parameters.Results: With increasing RV quintile, patients were younger, more frequently women, had lower forced expiratory volume in the first second%, lower body mass index and fat-free mass index, shorter 6MWD, shorter CWRT, and worse SGRQ scores (PConclusions: LH in COPD is related to younger age, female sex, lower body weight, worse exercise capacity and health status, but did not prevent patients from benefitting from PR. LH, however, influences walking and cycling response after PR differently. (C) 2018 by the American Congress of Rehabilitation Medicine
AB - Objective: To evaluate the effect of pulmonary rehabilitation (PR) on exercise performance and quality of life in patients with chronic obstructive pulmonary disease (COPD) with different degrees of static lung hyperinflation (LH).Design: Retrospective cohort study.Setting: PR network.Participants: A cohort of 1981 patients with COPD (55% men; age: 66.8 +/- 9.3y; forced expiratory volume in the first second%: 50.7 +/- 19.5; residual volume [RV]%: 163.0 +/- 49.7).Intervention: An interdisciplinary PR program for patients with COPD consisting of 40 sessions.Main Outcome Measures: Participants were stratified into 5 quintiles according to baseline RV and were evaluated on the basis of pre- and post - PR 6-minute walk distance (6MWD), constant work rate test (CWRT), and Saint George's Respiratory Questionnaire (SGRQ), among other clinical parameters.Results: With increasing RV quintile, patients were younger, more frequently women, had lower forced expiratory volume in the first second%, lower body mass index and fat-free mass index, shorter 6MWD, shorter CWRT, and worse SGRQ scores (PConclusions: LH in COPD is related to younger age, female sex, lower body weight, worse exercise capacity and health status, but did not prevent patients from benefitting from PR. LH, however, influences walking and cycling response after PR differently. (C) 2018 by the American Congress of Rehabilitation Medicine
KW - COPD
KW - Rehabilitation
KW - FIELD WALKING TESTS
KW - MUSCLE DYSFUNCTION
KW - EXERCISE PERFORMANCE
KW - NATIONAL EMPHYSEMA
KW - HEALTH-STATUS
KW - MECHANISMS
KW - CAPACITY
KW - IMPACT
U2 - 10.1016/j.apmr.2018.05.011
DO - 10.1016/j.apmr.2018.05.011
M3 - Article
C2 - 29906421
SN - 0003-9993
VL - 99
SP - 2279
EP - 2286
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 11
ER -