Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension

Stefan Engeli; Rudi Stinkens; Tim Heise; Marcus May; Gijs H. Goossens; Ellen E. Blaak; Bas Havekes; Thomas Jax; Diego Albrecht; Parasar Pal; Uwe Tegtbur; Sven Haufe; Thomas H. Langenickel; Jens Jordan

doi:10.1161/HYPERTENSIONAHA.117.10224

Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension

Stefan Engeli, Rudi Stinkens, Tim Heise, Marcus May, Gijs H. Goossens, Ellen E. Blaak, Bas Havekes, Thomas Jax, Diego Albrecht, Parasar Pal, Uwe Tegtbur, Sven Haufe, Thomas H. Langenickel, Jens Jordan

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	70-77
Number of pages	8
Journal	Hypertension
Volume	71
Issue number	1
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.117.10224
Publication status	Published - 1 Jan 2018

Keywords

exercise-induced lipolysis
hypertension
lipid metabolism
natriuretic peptide
neprilysin
obesity
sacubitril
valsartan
INTERSTITIAL ANGIOTENSIN-II
BRAIN NATRIURETIC PEPTIDE
TRIAL VAL-HEFT
HEART-FAILURE
INSULIN-RESISTANCE
NEPRILYSIN INHIBITION
GLUCOSE-METABOLISM
HUMAN ADIPOCYTES
ADIPOSE-TISSUE
NORMAL-WEIGHT
Obesity, Abdominal/diagnosis
Natriuretic Peptides/metabolism
Humans
Middle Aged
Male
Calcium Channel Blockers/administration & dosage
Adipose Tissue/metabolism
Female
Hypertension/diagnosis
Angiotensin Receptor Antagonists/administration & dosage
Double-Blind Method
Aminobutyrates/administration & dosage
Lipid Metabolism/drug effects
Amlodipine/administration & dosage
Exercise/physiology
Treatment Outcome
Neprilysin/antagonists & inhibitors
Drug Monitoring/methods
Tetrazoles/administration & dosage
Blood Pressure/drug effects

Access to Document

10.1161/HYPERTENSIONAHA.117.10224

Cite this

Engeli, S., Stinkens, R., Heise, T., May, M., Goossens, G. H., Blaak, E. E., Havekes, B., Jax, T., Albrecht, D., Pal, P., Tegtbur, U., Haufe, S., Langenickel, T. H., & Jordan, J. (2018). Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension. Hypertension, 71(1), 70-77. https://doi.org/10.1161/HYPERTENSIONAHA.117.10224

Engeli, Stefan ; Stinkens, Rudi ; Heise, Tim ; May, Marcus ; Goossens, Gijs H. ; Blaak, Ellen E. ; Havekes, Bas ; Jax, Thomas ; Albrecht, Diego ; Pal, Parasar ; Tegtbur, Uwe ; Haufe, Sven ; Langenickel, Thomas H. ; Jordan, Jens. / Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension. In: Hypertension. 2018 ; Vol. 71, No. 1. pp. 70-77.

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title = "Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension",

keywords = "exercise-induced lipolysis, hypertension, lipid metabolism, natriuretic peptide, neprilysin, obesity, sacubitril, valsartan, INTERSTITIAL ANGIOTENSIN-II, BRAIN NATRIURETIC PEPTIDE, TRIAL VAL-HEFT, HEART-FAILURE, INSULIN-RESISTANCE, NEPRILYSIN INHIBITION, GLUCOSE-METABOLISM, HUMAN ADIPOCYTES, ADIPOSE-TISSUE, NORMAL-WEIGHT, Obesity, Abdominal/diagnosis, Natriuretic Peptides/metabolism, Humans, Middle Aged, Male, Calcium Channel Blockers/administration & dosage, Adipose Tissue/metabolism, Female, Hypertension/diagnosis, Angiotensin Receptor Antagonists/administration & dosage, Double-Blind Method, Aminobutyrates/administration & dosage, Lipid Metabolism/drug effects, Amlodipine/administration & dosage, Exercise/physiology, Treatment Outcome, Neprilysin/antagonists & inhibitors, Drug Monitoring/methods, Tetrazoles/administration & dosage, Blood Pressure/drug effects",

author = "Stefan Engeli and Rudi Stinkens and Tim Heise and Marcus May and Goossens, {Gijs H.} and Blaak, {Ellen E.} and Bas Havekes and Thomas Jax and Diego Albrecht and Parasar Pal and Uwe Tegtbur and Sven Haufe and Langenickel, {Thomas H.} and Jens Jordan",

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doi = "10.1161/HYPERTENSIONAHA.117.10224",

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Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension. / Engeli, Stefan; Stinkens, Rudi; Heise, Tim; May, Marcus; Goossens, Gijs H.; Blaak, Ellen E.; Havekes, Bas; Jax, Thomas; Albrecht, Diego; Pal, Parasar; Tegtbur, Uwe; Haufe, Sven; Langenickel, Thomas H.; Jordan, Jens.

In: Hypertension, Vol. 71, No. 1, 01.01.2018, p. 70-77.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Engeli, Stefan

AU - Stinkens, Rudi

AU - Heise, Tim

AU - May, Marcus

AU - Goossens, Gijs H.

AU - Blaak, Ellen E.

AU - Havekes, Bas

AU - Jax, Thomas

AU - Albrecht, Diego

AU - Pal, Parasar

AU - Tegtbur, Uwe

AU - Haufe, Sven

AU - Langenickel, Thomas H.

AU - Jordan, Jens

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KW - BRAIN NATRIURETIC PEPTIDE

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KW - Double-Blind Method

KW - Aminobutyrates/administration & dosage

KW - Lipid Metabolism/drug effects

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KW - Treatment Outcome

KW - Neprilysin/antagonists & inhibitors

KW - Drug Monitoring/methods

KW - Tetrazoles/administration & dosage

KW - Blood Pressure/drug effects

U2 - 10.1161/HYPERTENSIONAHA.117.10224

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