Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension

Stefan Engeli, Rudi Stinkens, Tim Heise, Marcus May, Gijs H. Goossens, Ellen E. Blaak, Bas Havekes, Thomas Jax, Diego Albrecht, Parasar Pal, Uwe Tegtbur, Sven Haufe, Thomas H. Langenickel, Jens Jordan

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)70-77
Number of pages8
JournalHypertension
Volume71
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • exercise-induced lipolysis
  • hypertension
  • lipid metabolism
  • natriuretic peptide
  • neprilysin
  • obesity
  • sacubitril
  • valsartan
  • INTERSTITIAL ANGIOTENSIN-II
  • BRAIN NATRIURETIC PEPTIDE
  • TRIAL VAL-HEFT
  • HEART-FAILURE
  • INSULIN-RESISTANCE
  • NEPRILYSIN INHIBITION
  • GLUCOSE-METABOLISM
  • HUMAN ADIPOCYTES
  • ADIPOSE-TISSUE
  • NORMAL-WEIGHT
  • Obesity, Abdominal/diagnosis
  • Natriuretic Peptides/metabolism
  • Humans
  • Middle Aged
  • Male
  • Calcium Channel Blockers/administration & dosage
  • Adipose Tissue/metabolism
  • Female
  • Hypertension/diagnosis
  • Angiotensin Receptor Antagonists/administration & dosage
  • Double-Blind Method
  • Aminobutyrates/administration & dosage
  • Lipid Metabolism/drug effects
  • Amlodipine/administration & dosage
  • Exercise/physiology
  • Treatment Outcome
  • Neprilysin/antagonists & inhibitors
  • Drug Monitoring/methods
  • Tetrazoles/administration & dosage
  • Blood Pressure/drug effects

Cite this

Engeli, S., Stinkens, R., Heise, T., May, M., Goossens, G. H., Blaak, E. E., Havekes, B., Jax, T., Albrecht, D., Pal, P., Tegtbur, U., Haufe, S., Langenickel, T. H., & Jordan, J. (2018). Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension. Hypertension, 71(1), 70-77. https://doi.org/10.1161/HYPERTENSIONAHA.117.10224