Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells

Q. Shi, A. W. Boots, L. Maas, C. Veith, K. van Kuijk, G. R. Haenen, R. W. Godschalk, F. J. Van Schooten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)64-74
Number of pages11
JournalToxicology
Volume381
DOIs
Publication statusPublished - 15 Apr 2017

Keywords

  • Benzo[a]pyrene (B[a]P)
  • Interleukin (IL)-8
  • NADPH-dependent cytochrome P450s 1A1/
  • 1B1 (CYP1A1/CYP1B1)
  • NADPH oxidase pathway (NOX)
  • Glutathione (GSH)
  • DNA adducts
  • NUCLEOTIDE EXCISION-REPAIR
  • FACTOR-KAPPA-B
  • POLYCYCLIC AROMATIC-HYDROCARBONS
  • OBSTRUCTIVE PULMONARY-DISEASE
  • OXIDATIVE STRESS
  • INFLAMMATORY RESPONSE
  • TRANSCRIPTION FACTOR
  • AIRWAY INFLAMMATION
  • GENE-EXPRESSION
  • ADDUCT LEVELS

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