Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells

Q. Shi, A. W. Boots, L. Maas, C. Veith, K. van Kuijk, G. R. Haenen, R. W. Godschalk, F. J. Van Schooten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)64-74
Number of pages11
JournalToxicology
Volume381
DOIs
Publication statusPublished - 15 Apr 2017

Keywords

  • Benzo[a]pyrene (B[a]P)
  • Interleukin (IL)-8
  • NADPH-dependent cytochrome P450s 1A1/
  • 1B1 (CYP1A1/CYP1B1)
  • NADPH oxidase pathway (NOX)
  • Glutathione (GSH)
  • DNA adducts
  • NUCLEOTIDE EXCISION-REPAIR
  • FACTOR-KAPPA-B
  • POLYCYCLIC AROMATIC-HYDROCARBONS
  • OBSTRUCTIVE PULMONARY-DISEASE
  • OXIDATIVE STRESS
  • INFLAMMATORY RESPONSE
  • TRANSCRIPTION FACTOR
  • AIRWAY INFLAMMATION
  • GENE-EXPRESSION
  • ADDUCT LEVELS

Cite this

@article{4204c007aa2b4266be35446570d4a5b4,
title = "Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells",
keywords = "Benzo[a]pyrene (B[a]P), Interleukin (IL)-8, NADPH-dependent cytochrome P450s 1A1/, 1B1 (CYP1A1/CYP1B1), NADPH oxidase pathway (NOX), Glutathione (GSH), DNA adducts, NUCLEOTIDE EXCISION-REPAIR, FACTOR-KAPPA-B, POLYCYCLIC AROMATIC-HYDROCARBONS, OBSTRUCTIVE PULMONARY-DISEASE, OXIDATIVE STRESS, INFLAMMATORY RESPONSE, TRANSCRIPTION FACTOR, AIRWAY INFLAMMATION, GENE-EXPRESSION, ADDUCT LEVELS",
author = "Q. Shi and Boots, {A. W.} and L. Maas and C. Veith and {van Kuijk}, K. and Haenen, {G. R.} and Godschalk, {R. W.} and {Van Schooten}, {F. J.}",
year = "2017",
month = "4",
day = "15",
doi = "10.1016/j.tox.2017.02.013",
language = "English",
volume = "381",
pages = "64--74",
journal = "Toxicology",
issn = "0300-483X",
publisher = "Elsevier Ireland Ltd",

}

Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells. / Shi, Q.; Boots, A. W.; Maas, L.; Veith, C.; van Kuijk, K.; Haenen, G. R.; Godschalk, R. W.; Van Schooten, F. J.

In: Toxicology, Vol. 381, 15.04.2017, p. 64-74.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells

AU - Shi, Q.

AU - Boots, A. W.

AU - Maas, L.

AU - Veith, C.

AU - van Kuijk, K.

AU - Haenen, G. R.

AU - Godschalk, R. W.

AU - Van Schooten, F. J.

PY - 2017/4/15

Y1 - 2017/4/15

KW - Benzo[a]pyrene (B[a]P)

KW - Interleukin (IL)-8

KW - NADPH-dependent cytochrome P450s 1A1/

KW - 1B1 (CYP1A1/CYP1B1)

KW - NADPH oxidase pathway (NOX)

KW - Glutathione (GSH)

KW - DNA adducts

KW - NUCLEOTIDE EXCISION-REPAIR

KW - FACTOR-KAPPA-B

KW - POLYCYCLIC AROMATIC-HYDROCARBONS

KW - OBSTRUCTIVE PULMONARY-DISEASE

KW - OXIDATIVE STRESS

KW - INFLAMMATORY RESPONSE

KW - TRANSCRIPTION FACTOR

KW - AIRWAY INFLAMMATION

KW - GENE-EXPRESSION

KW - ADDUCT LEVELS

U2 - 10.1016/j.tox.2017.02.013

DO - 10.1016/j.tox.2017.02.013

M3 - Article

VL - 381

SP - 64

EP - 74

JO - Toxicology

JF - Toxicology

SN - 0300-483X

ER -