Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial

Wes Onland; Filip Cools; Andre Kroon; Karin Rademaker; Maruschka P. Merkus; Peter H. Dijk; Henrica L. van Straaten; Arjan B. Te Pas; Thilo Mohns; Els Bruneel; Arno F. van Heijst; Boris W. Kramer; Anne Debeer; Inge Zonnenberg; Yoann Marechal; Henry Blom; Katleen Plaskie; Martin Offringa; Anton H. van Kaam; Debbie H. Nuytemans; Moniek van de Loo; E. Marleen Kemper; Inez Vereeck; Marja van der Heide-Jalving; Ellen de Kort; Eric Cavartorta; Anne Rassart; An Eerdekens; Margriet Stuijvenberg; Rene Matthijsse; Willem de Boode; Hendrik Niemarkt; Ilse van Hattum; Liesbeth Groot Jebbink; Susanne M. Mulder-de Tollenaer; Ratna Tan; Claire Theyskens; Mirjam van Weissenbruch; Elke Dierckx; Vincent Rigo; Elianne Vrijlandt; Ingeborg van der Tweel; Caroline van Baal; Saskia de Wildt; STOP-BPD Study Grp; Data Safety Monitoring Comm

doi:10.1001/jama.2018.21443

Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial

Wes Onland, Filip Cools, Andre Kroon, Karin Rademaker, Maruschka P. Merkus, Peter H. Dijk, Henrica L. van Straaten, Arjan B. Te Pas, Thilo Mohns, Els Bruneel, Arno F. van Heijst, Boris W. Kramer, Anne Debeer, Inge Zonnenberg, Yoann Marechal, Henry Blom, Katleen Plaskie, Martin Offringa, Anton H. van Kaam^*, Debbie H. NuytemansMoniek van de Loo, E. Marleen Kemper, Inez Vereeck, Marja van der Heide-Jalving, Ellen de Kort, Eric Cavartorta, Anne Rassart, An Eerdekens, Margriet Stuijvenberg, Rene Matthijsse, Willem de Boode, Hendrik Niemarkt, Ilse van Hattum, Liesbeth Groot Jebbink, Susanne M. Mulder-de Tollenaer, Ratna Tan, Claire Theyskens, Mirjam van Weissenbruch, Elke Dierckx, Vincent Rigo, Elianne Vrijlandt, Ingeborg van der Tweel, Caroline van Baal, Saskia de Wildt, STOP-BPD Study Grp, Data Safety Monitoring Comm

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	354-363
Number of pages	10
Journal	JAMA-Journal of the American Medical Association
Volume	321
Issue number	4
DOIs	https://doi.org/10.1001/jama.2018.21443
Publication status	Published - 29 Jan 2019

Keywords

POSTNATAL CORTICOSTEROIDS
RISK-FACTORS
MORBIDITY
CHILDREN
PREVENT
TREAT

Access to Document

10.1001/jama.2018.21443

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Onland, W., Cools, F., Kroon, A., Rademaker, K., Merkus, M. P., Dijk, P. H., van Straaten, H. L., Pas, A. B. T., Mohns, T., Bruneel, E., van Heijst, A. F., Kramer, B. W., Debeer, A., Zonnenberg, I., Marechal, Y., Blom, H., Plaskie, K., Offringa, M., van Kaam, A. H., ... Data Safety Monitoring Comm (2019). Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial. JAMA-Journal of the American Medical Association, 321(4), 354-363. https://doi.org/10.1001/jama.2018.21443

Onland, Wes ; Cools, Filip ; Kroon, Andre ; Rademaker, Karin ; Merkus, Maruschka P. ; Dijk, Peter H. ; van Straaten, Henrica L. ; Pas, Arjan B. Te ; Mohns, Thilo ; Bruneel, Els ; van Heijst, Arno F. ; Kramer, Boris W. ; Debeer, Anne ; Zonnenberg, Inge ; Marechal, Yoann ; Blom, Henry ; Plaskie, Katleen ; Offringa, Martin ; van Kaam, Anton H. ; Nuytemans, Debbie H. ; de Loo, Moniek van ; Kemper, E. Marleen ; Vereeck, Inez ; van der Heide-Jalving, Marja ; de Kort, Ellen ; Cavartorta, Eric ; Rassart, Anne ; Eerdekens, An ; Stuijvenberg, Margriet ; Matthijsse, Rene ; de Boode, Willem ; Niemarkt, Hendrik ; van Hattum, Ilse ; Jebbink, Liesbeth Groot ; Mulder-de Tollenaer, Susanne M. ; Tan, Ratna ; Theyskens, Claire ; van Weissenbruch, Mirjam ; Dierckx, Elke ; Rigo, Vincent ; Vrijlandt, Elianne ; van der Tweel, Ingeborg ; van Baal, Caroline ; de Wildt, Saskia ; STOP-BPD Study Grp ; Data Safety Monitoring Comm. / Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation : A Randomized Clinical Trial. In: JAMA-Journal of the American Medical Association. 2019 ; Vol. 321, No. 4. pp. 354-363.

@article{a0f015d7bb58478e989ee7cf9c49010b,

title = "Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial",

keywords = "POSTNATAL CORTICOSTEROIDS, RISK-FACTORS, MORBIDITY, CHILDREN, PREVENT, TREAT",

author = "Wes Onland and Filip Cools and Andre Kroon and Karin Rademaker and Merkus, {Maruschka P.} and Dijk, {Peter H.} and {van Straaten}, {Henrica L.} and Pas, {Arjan B. Te} and Thilo Mohns and Els Bruneel and {van Heijst}, {Arno F.} and Kramer, {Boris W.} and Anne Debeer and Inge Zonnenberg and Yoann Marechal and Henry Blom and Katleen Plaskie and Martin Offringa and {van Kaam}, {Anton H.} and Nuytemans, {Debbie H.} and {de Loo}, {Moniek van} and Kemper, {E. Marleen} and Inez Vereeck and {van der Heide-Jalving}, Marja and {de Kort}, Ellen and Eric Cavartorta and Anne Rassart and An Eerdekens and Margriet Stuijvenberg and Rene Matthijsse and {de Boode}, Willem and Hendrik Niemarkt and {van Hattum}, Ilse and Jebbink, {Liesbeth Groot} and {Mulder-de Tollenaer}, {Susanne M.} and Ratna Tan and Claire Theyskens and {van Weissenbruch}, Mirjam and Elke Dierckx and Vincent Rigo and Elianne Vrijlandt and {van der Tweel}, Ingeborg and {van Baal}, Caroline and {de Wildt}, Saskia and {STOP-BPD Study Grp} and {Data Safety Monitoring Comm}",

year = "2019",

month = jan,

day = "29",

doi = "10.1001/jama.2018.21443",

language = "English",

volume = "321",

pages = "354--363",

journal = "JAMA-Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

number = "4",

}

Onland, W, Cools, F, Kroon, A, Rademaker, K, Merkus, MP, Dijk, PH, van Straaten, HL, Pas, ABT, Mohns, T, Bruneel, E, van Heijst, AF, Kramer, BW, Debeer, A, Zonnenberg, I, Marechal, Y, Blom, H, Plaskie, K, Offringa, M, van Kaam, AH, Nuytemans, DH, de Loo, MV, Kemper, EM, Vereeck, I, van der Heide-Jalving, M, de Kort, E, Cavartorta, E, Rassart, A, Eerdekens, A, Stuijvenberg, M, Matthijsse, R, de Boode, W, Niemarkt, H, van Hattum, I, Jebbink, LG, Mulder-de Tollenaer, SM, Tan, R, Theyskens, C, van Weissenbruch, M, Dierckx, E, Rigo, V, Vrijlandt, E, van der Tweel, I, van Baal, C, de Wildt, S, STOP-BPD Study Grp & Data Safety Monitoring Comm 2019, 'Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial', JAMA-Journal of the American Medical Association, vol. 321, no. 4, pp. 354-363. https://doi.org/10.1001/jama.2018.21443

Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation : A Randomized Clinical Trial. / Onland, Wes; Cools, Filip; Kroon, Andre; Rademaker, Karin; Merkus, Maruschka P.; Dijk, Peter H.; van Straaten, Henrica L.; Pas, Arjan B. Te; Mohns, Thilo; Bruneel, Els; van Heijst, Arno F.; Kramer, Boris W.; Debeer, Anne; Zonnenberg, Inge; Marechal, Yoann; Blom, Henry; Plaskie, Katleen; Offringa, Martin; van Kaam, Anton H.; Nuytemans, Debbie H.; de Loo, Moniek van; Kemper, E. Marleen; Vereeck, Inez; van der Heide-Jalving, Marja; de Kort, Ellen; Cavartorta, Eric; Rassart, Anne; Eerdekens, An; Stuijvenberg, Margriet; Matthijsse, Rene; de Boode, Willem; Niemarkt, Hendrik; van Hattum, Ilse; Jebbink, Liesbeth Groot; Mulder-de Tollenaer, Susanne M.; Tan, Ratna; Theyskens, Claire; van Weissenbruch, Mirjam; Dierckx, Elke; Rigo, Vincent; Vrijlandt, Elianne; van der Tweel, Ingeborg; van Baal, Caroline; de Wildt, Saskia; STOP-BPD Study Grp; Data Safety Monitoring Comm.

In: JAMA-Journal of the American Medical Association, Vol. 321, No. 4, 29.01.2019, p. 354-363.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation

T2 - A Randomized Clinical Trial

AU - Onland, Wes

AU - Cools, Filip

AU - Kroon, Andre

AU - Rademaker, Karin

AU - Merkus, Maruschka P.

AU - Dijk, Peter H.

AU - van Straaten, Henrica L.

AU - Pas, Arjan B. Te

AU - Mohns, Thilo

AU - Bruneel, Els

AU - van Heijst, Arno F.

AU - Kramer, Boris W.

AU - Debeer, Anne

AU - Zonnenberg, Inge

AU - Marechal, Yoann

AU - Blom, Henry

AU - Plaskie, Katleen

AU - Offringa, Martin

AU - van Kaam, Anton H.

AU - Nuytemans, Debbie H.

AU - de Loo, Moniek van

AU - Kemper, E. Marleen

AU - Vereeck, Inez

AU - van der Heide-Jalving, Marja

AU - de Kort, Ellen

AU - Cavartorta, Eric

AU - Rassart, Anne

AU - Eerdekens, An

AU - Stuijvenberg, Margriet

AU - Matthijsse, Rene

AU - de Boode, Willem

AU - Niemarkt, Hendrik

AU - van Hattum, Ilse

AU - Jebbink, Liesbeth Groot

AU - Mulder-de Tollenaer, Susanne M.

AU - Tan, Ratna

AU - Theyskens, Claire

AU - van Weissenbruch, Mirjam

AU - Dierckx, Elke

AU - Rigo, Vincent

AU - Vrijlandt, Elianne

AU - van der Tweel, Ingeborg

AU - van Baal, Caroline

AU - de Wildt, Saskia

AU - STOP-BPD Study Grp

AU - Data Safety Monitoring Comm

PY - 2019/1/29

Y1 - 2019/1/29

KW - POSTNATAL CORTICOSTEROIDS

KW - RISK-FACTORS

KW - MORBIDITY

KW - CHILDREN

KW - PREVENT

KW - TREAT

U2 - 10.1001/jama.2018.21443

DO - 10.1001/jama.2018.21443

M3 - Article

C2 - 30694322

VL - 321

SP - 354

EP - 363

JO - JAMA-Journal of the American Medical Association

JF - JAMA-Journal of the American Medical Association

SN - 0098-7484

IS - 4

ER -

Onland W, Cools F, Kroon A, Rademaker K, Merkus MP, Dijk PH et al. Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial. JAMA-Journal of the American Medical Association. 2019 Jan 29;321(4):354-363. https://doi.org/10.1001/jama.2018.21443