Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors

Christian Rolfo; Helen Swaisland; Karin Leunen; Annemie Rutten; Patricia Soetekouw; Sarah Slater; Henk M. W. Verheul; Anitra Fielding; Karen So; Wendy Bannister; Emma Dean

doi:10.1007/s12325-015-0214-4

Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors

Christian Rolfo, Helen Swaisland, Karin Leunen, Annemie Rutten, Patricia Soetekouw, Sarah Slater, Henk M. W. Verheul, Anitra Fielding, Karen So, Wendy Bannister, Emma Dean

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	510-522
Journal	Advances in Therapy
Volume	32
Issue number	6
DOIs	https://doi.org/10.1007/s12325-015-0214-4
Publication status	Published - Jun 2015

Keywords

Food effect
Olaparib
Olaparib capsule
PARP inhibition
Pharmacokinetics
PK
Poly(ADP-ribose) polymerase (PARP) inhibitor

Access to Document

10.1007/s12325-015-0214-4

Cite this

Rolfo, Christian ; Swaisland, Helen ; Leunen, Karin ; Rutten, Annemie ; Soetekouw, Patricia ; Slater, Sarah ; Verheul, Henk M. W. ; Fielding, Anitra ; So, Karen ; Bannister, Wendy ; Dean, Emma. / Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors. In: Advances in Therapy. 2015 ; Vol. 32, No. 6. pp. 510-522.

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title = "Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors",

keywords = "Food effect, Olaparib, Olaparib capsule, PARP inhibition, Pharmacokinetics, PK, Poly(ADP-ribose) polymerase (PARP) inhibitor",

author = "Christian Rolfo and Helen Swaisland and Karin Leunen and Annemie Rutten and Patricia Soetekouw and Sarah Slater and Verheul, {Henk M. W.} and Anitra Fielding and Karen So and Wendy Bannister and Emma Dean",

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Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors. / Rolfo, Christian; Swaisland, Helen; Leunen, Karin; Rutten, Annemie; Soetekouw, Patricia; Slater, Sarah; Verheul, Henk M. W.; Fielding, Anitra; So, Karen; Bannister, Wendy; Dean, Emma.

In: Advances in Therapy, Vol. 32, No. 6, 06.2015, p. 510-522.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors

AU - Rolfo, Christian

AU - Swaisland, Helen

AU - Leunen, Karin

AU - Rutten, Annemie

AU - Soetekouw, Patricia

AU - Slater, Sarah

AU - Verheul, Henk M. W.

AU - Fielding, Anitra

AU - So, Karen

AU - Bannister, Wendy

AU - Dean, Emma

PY - 2015/6

Y1 - 2015/6

KW - Food effect

KW - Olaparib

KW - Olaparib capsule

KW - PARP inhibition

KW - Pharmacokinetics

KW - PK

KW - Poly(ADP-ribose) polymerase (PARP) inhibitor

U2 - 10.1007/s12325-015-0214-4

DO - 10.1007/s12325-015-0214-4

M3 - Article

VL - 32

SP - 510

EP - 522

JO - Advances in Therapy

JF - Advances in Therapy

SN - 0741-238X

IS - 6

ER -