Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors

Christian Rolfo; Helen Swaisland; Karin Leunen; Annemie Rutten; Patricia Soetekouw; Sarah Slater; Henk M. W. Verheul; Anitra Fielding; Karen So; Wendy Bannister; Emma Dean

doi:10.1007/s12325-015-0214-4

Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors

Christian Rolfo^*, Helen Swaisland, Karin Leunen, Annemie Rutten, Patricia Soetekouw, Sarah Slater, Henk M. W. Verheul, Anitra Fielding, Karen So, Wendy Bannister, Emma Dean

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	510-522
Journal	Advances in Therapy
Volume	32
Issue number	6
DOIs	https://doi.org/10.1007/s12325-015-0214-4
Publication status	Published - Jun 2015

Keywords

Food effect
Olaparib
Olaparib capsule
PARP inhibition
Pharmacokinetics
PK
Poly(ADP-ribose) polymerase (PARP) inhibitor

Access to Document

10.1007/s12325-015-0214-4

Cite this

Rolfo, Christian ; Swaisland, Helen ; Leunen, Karin ; Rutten, Annemie ; Soetekouw, Patricia ; Slater, Sarah ; Verheul, Henk M. W. ; Fielding, Anitra ; So, Karen ; Bannister, Wendy ; Dean, Emma. / Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors. In: Advances in Therapy. 2015 ; Vol. 32, No. 6. pp. 510-522.

@article{fff7c687ce1047e3be19926c5aa165fa,

title = "Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors",

keywords = "Food effect, Olaparib, Olaparib capsule, PARP inhibition, Pharmacokinetics, PK, Poly(ADP-ribose) polymerase (PARP) inhibitor",

author = "Christian Rolfo and Helen Swaisland and Karin Leunen and Annemie Rutten and Patricia Soetekouw and Sarah Slater and Verheul, {Henk M. W.} and Anitra Fielding and Karen So and Wendy Bannister and Emma Dean",

year = "2015",

month = jun,

doi = "10.1007/s12325-015-0214-4",

language = "English",

volume = "32",

pages = "510--522",

journal = "Advances in Therapy",

issn = "0741-238X",

publisher = "Springer",

number = "6",

}

Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors. / Rolfo, Christian; Swaisland, Helen; Leunen, Karin; Rutten, Annemie; Soetekouw, Patricia; Slater, Sarah; Verheul, Henk M. W.; Fielding, Anitra; So, Karen; Bannister, Wendy; Dean, Emma.

In: Advances in Therapy, Vol. 32, No. 6, 06.2015, p. 510-522.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors

AU - Rolfo, Christian

AU - Swaisland, Helen

AU - Leunen, Karin

AU - Rutten, Annemie

AU - Soetekouw, Patricia

AU - Slater, Sarah

AU - Verheul, Henk M. W.

AU - Fielding, Anitra

AU - So, Karen

AU - Bannister, Wendy

AU - Dean, Emma

PY - 2015/6

Y1 - 2015/6

KW - Food effect

KW - Olaparib

KW - Olaparib capsule

KW - PARP inhibition

KW - Pharmacokinetics

KW - PK

KW - Poly(ADP-ribose) polymerase (PARP) inhibitor

U2 - 10.1007/s12325-015-0214-4

DO - 10.1007/s12325-015-0214-4

M3 - Article

C2 - 26048134

VL - 32

SP - 510

EP - 522

JO - Advances in Therapy

JF - Advances in Therapy

SN - 0741-238X

IS - 6

ER -