Effect of 1 Year Krill Oil Supplementation on Cognitive Achievement of Dutch Adolescents: A Double-Blind Randomized Controlled Trial

Inge S. M. van der Wurff; Clemens von Schacky; Trygve Bergeland; Roeslan Leontjevas; Maurice P. Zeegers; Jelle Jolles; Paul A. Kirschner; Renate H. M. de Groot

doi:10.3390/nu11061230

Effect of 1 Year Krill Oil Supplementation on Cognitive Achievement of Dutch Adolescents: A Double-Blind Randomized Controlled Trial

Inge S. M. van der Wurff^*
, Clemens von Schacky
, Trygve Bergeland
, Roeslan Leontjevas
, Maurice P. Zeegers
, Jelle Jolles
, Paul A. Kirschner
, Renate H. M. de Groot

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Long-chain polyunsaturated fatty acids (LCPUFA) are important for brain development and function, maybe especially during adolescence. Observational studies have demonstrated an association between fish consumption (a source of LCPUFA) and cognition in adolescents, but intervention trials are lacking. The goal of the current study was to investigate the effect of one year of krill oil (a source of LCPUFA) supplementation on the cognitive performance of adolescents with a low Omega-3 Index (O3I

Original language	English
Article number	1230
Pages (from-to)	1-15
Number of pages	15
Journal	Nutrients
Volume	11
Issue number	6
DOIs	https://doi.org/10.3390/nu11061230
Publication status	Published - Jun 2019

Keywords

docosahexaenoic acid (DHA)
eicosapentaenoic acid (EPA)
adolescents
cognition
omega-3 fatty acids
omega-3 Index
krill oil
randomized controlled trial (RCT)
fatty acids
POLYUNSATURATED FATTY-ACIDS
DIGIT SUBSTITUTION TEST
DOCOSAHEXAENOIC ACID
FISH CONSUMPTION
NORMATIVE DATA
CHILDREN
PLACEBO
OMEGA-3
HEALTHY
PERFORMANCE

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@article{994583aaf3294fd9808f9d3d1eb27a01,

title = "Effect of 1 Year Krill Oil Supplementation on Cognitive Achievement of Dutch Adolescents: A Double-Blind Randomized Controlled Trial",

abstract = "Long-chain polyunsaturated fatty acids (LCPUFA) are important for brain development and function, maybe especially during adolescence. Observational studies have demonstrated an association between fish consumption (a source of LCPUFA) and cognition in adolescents, but intervention trials are lacking. The goal of the current study was to investigate the effect of one year of krill oil (a source of LCPUFA) supplementation on the cognitive performance of adolescents with a low Omega-3 Index (O3I",

keywords = "docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), adolescents, cognition, omega-3 fatty acids, omega-3 Index, krill oil, randomized controlled trial (RCT), fatty acids, POLYUNSATURATED FATTY-ACIDS, DIGIT SUBSTITUTION TEST, DOCOSAHEXAENOIC ACID, FISH CONSUMPTION, NORMATIVE DATA, CHILDREN, PLACEBO, OMEGA-3, HEALTHY, PERFORMANCE",

author = "\{van der Wurff\}, \{Inge S. M.\} and \{von Schacky\}, Clemens and Trygve Bergeland and Roeslan Leontjevas and Zeegers, \{Maurice P.\} and Jelle Jolles and Kirschner, \{Paul A.\} and \{de Groot\}, \{Renate H. M.\}",

note = "Funding Information: Funding: This research was partly funded by The Netherlands Organization for Scientific Research grant number [057-13-002] and by AkerBiomarine. Publisher Copyright: {\textcopyright} 2019, MDPI AG. All rights reserved.",

year = "2019",

month = jun,

doi = "10.3390/nu11061230",

language = "English",

volume = "11",

pages = "1--15",

journal = "Nutrients",

issn = "2072-6643",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "6",

}

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T1 - Effect of 1 Year Krill Oil Supplementation on Cognitive Achievement of Dutch Adolescents

T2 - A Double-Blind Randomized Controlled Trial

AU - van der Wurff, Inge S. M.

AU - von Schacky, Clemens

AU - Bergeland, Trygve

AU - Leontjevas, Roeslan

AU - Zeegers, Maurice P.

AU - Jolles, Jelle

AU - Kirschner, Paul A.

AU - de Groot, Renate H. M.

N1 - Funding Information: Funding: This research was partly funded by The Netherlands Organization for Scientific Research grant number [057-13-002] and by AkerBiomarine. Publisher Copyright: © 2019, MDPI AG. All rights reserved.

PY - 2019/6

Y1 - 2019/6

N2 - Long-chain polyunsaturated fatty acids (LCPUFA) are important for brain development and function, maybe especially during adolescence. Observational studies have demonstrated an association between fish consumption (a source of LCPUFA) and cognition in adolescents, but intervention trials are lacking. The goal of the current study was to investigate the effect of one year of krill oil (a source of LCPUFA) supplementation on the cognitive performance of adolescents with a low Omega-3 Index (O3I

AB - Long-chain polyunsaturated fatty acids (LCPUFA) are important for brain development and function, maybe especially during adolescence. Observational studies have demonstrated an association between fish consumption (a source of LCPUFA) and cognition in adolescents, but intervention trials are lacking. The goal of the current study was to investigate the effect of one year of krill oil (a source of LCPUFA) supplementation on the cognitive performance of adolescents with a low Omega-3 Index (O3I

KW - docosahexaenoic acid (DHA)

KW - eicosapentaenoic acid (EPA)

KW - adolescents

KW - cognition

KW - omega-3 fatty acids

KW - omega-3 Index

KW - krill oil

KW - randomized controlled trial (RCT)

KW - fatty acids

KW - POLYUNSATURATED FATTY-ACIDS

KW - DIGIT SUBSTITUTION TEST

KW - DOCOSAHEXAENOIC ACID

KW - FISH CONSUMPTION

KW - NORMATIVE DATA

KW - CHILDREN

KW - PLACEBO

KW - OMEGA-3

KW - HEALTHY

KW - PERFORMANCE

U2 - 10.3390/nu11061230

DO - 10.3390/nu11061230

M3 - Article

C2 - 31151199

SN - 2072-6643

VL - 11

SP - 1

EP - 15

JO - Nutrients

JF - Nutrients

IS - 6

M1 - 1230

ER -

Effect of 1 Year Krill Oil Supplementation on Cognitive Achievement of Dutch Adolescents: A Double-Blind Randomized Controlled Trial

Abstract

Keywords

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