TY - JOUR
T1 - Effect modification of the short-term effects of air pollution on morbidity by season: A systematic review and meta-analysis
AU - Bergmann, Stephanie
AU - Li, Bixia
AU - Pilot, Eva
AU - Chen, Renchao
AU - Wang, Boguang
AU - Yang, Jun
N1 - Funding Information:
The study was supported by the Fundamental Research Funds for the Central Universities (No. 11618323 ), Natural Science Foundation of Guangdong Province (No. 2018A030310655 ), the National Key Research and Development Program of China (No. 2018YFC0213602 ), and the Guangdong Provincial Science and Technology Planning Project of China (No. 2017B050504002 ).
Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2020/5/10
Y1 - 2020/5/10
N2 - Studies of the health effects of air pollution have traditionally controlled for ambient temperature as a confounder, and vice versa. However, season might be an important factor contributing to adverse health effects of air pollution. Given the current inconsistencies in results of previous studies on the effect modification of air pollution on morbidity by season, a systematic review and meta-analysis was conducted to synthesize the current evidence on effects of season on air pollution and morbidity. The electronic databases including PubMed, Web of Science, Embase, CNKI, and Wanfang were used to identify papers published up to the 30st of November in 2019. We identified 4284 articles, after screening, eighty papers met the inclusion criteria. Significant effect modification of CO, O3, SO2 and NO2 on morbidity by season was observed, with corresponding ratio of relative risk of 1.0009 (95% CI: 1.0001–1.0018), 1.0080 (95% CI: 1.0021–1.0138), 0.9828 (95% CI: 0.9697–0.9962) and 0.9896 (95% CI: 0.9824–0.9968), respectively. Season significantly modified the effect of CO on pneumonia, the effect of SO2 on cardiovascular disease, the effect of PM10 on stroke, and the effect of O3 on stroke, asthma and pneumonia. The effect modifications of air pollution by season were similar among males and females, while the effect estimates seem to be higher among children under 18 years old and the elderly aged 75 or over. Further research is needed to better understand the mechanisms underlying the seasonal variance of the effect of air pollutants on morbidity.
AB - Studies of the health effects of air pollution have traditionally controlled for ambient temperature as a confounder, and vice versa. However, season might be an important factor contributing to adverse health effects of air pollution. Given the current inconsistencies in results of previous studies on the effect modification of air pollution on morbidity by season, a systematic review and meta-analysis was conducted to synthesize the current evidence on effects of season on air pollution and morbidity. The electronic databases including PubMed, Web of Science, Embase, CNKI, and Wanfang were used to identify papers published up to the 30st of November in 2019. We identified 4284 articles, after screening, eighty papers met the inclusion criteria. Significant effect modification of CO, O3, SO2 and NO2 on morbidity by season was observed, with corresponding ratio of relative risk of 1.0009 (95% CI: 1.0001–1.0018), 1.0080 (95% CI: 1.0021–1.0138), 0.9828 (95% CI: 0.9697–0.9962) and 0.9896 (95% CI: 0.9824–0.9968), respectively. Season significantly modified the effect of CO on pneumonia, the effect of SO2 on cardiovascular disease, the effect of PM10 on stroke, and the effect of O3 on stroke, asthma and pneumonia. The effect modifications of air pollution by season were similar among males and females, while the effect estimates seem to be higher among children under 18 years old and the elderly aged 75 or over. Further research is needed to better understand the mechanisms underlying the seasonal variance of the effect of air pollutants on morbidity.
KW - air pollution
KW - meta analysis
KW - morbidity
KW - season
KW - systematic review
KW - EMERGENCY-DEPARTMENT VISITS
KW - DAILY HOSPITAL ADMISSIONS
KW - Systematic review
KW - PARTICULATE MATTER POLLUTION
KW - Morbidity
KW - Meta-analysis
KW - ASTHMA HOSPITALIZATION
KW - OBSTRUCTIVE PULMONARY-DISEASE
KW - MENTAL-DISORDERS
KW - Effect modification
KW - TIME-SERIES
KW - RESPIRATORY MORBIDITY
KW - OUTPATIENT VISITS
KW - Air pollution
KW - Season
KW - ACUTE EXACERBATION
U2 - 10.1016/j.scitotenv.2020.136985
DO - 10.1016/j.scitotenv.2020.136985
M3 - Article
C2 - 32044481
SN - 0048-9697
VL - 716
JO - Science of the Total Environment
JF - Science of the Total Environment
IS - 136985
M1 - 136985
ER -