Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial)

Tim Hundscheid, Wes Onland, Bart van Overmeire, Peter Dijk, Anton H. L. C. van Kaam, Koen P. Dijkman, Elisabeth M. W. Kooi, Eduardo Villamor, Andre A. Kroon, Remco Visser, Daniel C. Vijlbrief, Susanne M. de Tollenaer, Filip Cools, David van Laere, Anne-Britt Johansson, Catheline Hocq, Alexandra Zecic, Eddy Adang, Rogier Donders, Willem de VriesArno F. J. van Heijst, Willem P. de Boode

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number262
Number of pages14
JournalBmc Pediatrics
Volume18
DOIs
Publication statusPublished - 4 Aug 2018

Keywords

  • Prematurity
  • Patent ductus arteriosus
  • Neonatal intensive care unit
  • Ibuprofen
  • Expectative management
  • Ductal ligation
  • Mortality
  • Necrotising enterocolitis
  • Bronchopulmonary dysplasia
  • Cost-effectiveness
  • LOW-BIRTH-WEIGHT
  • PLACEBO-CONTROLLED TRIAL
  • PROPHYLACTIC INDOMETHACIN THERAPY
  • RESPIRATORY-DISTRESS SYNDROME
  • BUDGET IMPACT ANALYSIS
  • PREMATURE-INFANTS
  • DOUBLE-BLIND
  • INTRAVENOUS IBUPROFEN
  • EARLY CLOSURE
  • BLOOD-FLOW

Cite this

Hundscheid, T., Onland, W., van Overmeire, B., Dijk, P., van Kaam, A. H. L. C., Dijkman, K. P., Kooi, E. M. W., Villamor, E., Kroon, A. A., Visser, R., Vijlbrief, D. C., de Tollenaer, S. M., Cools, F., van Laere, D., Johansson, A-B., Hocq, C., Zecic, A., Adang, E., Donders, R., ... de Boode, W. P. (2018). Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial). Bmc Pediatrics, 18, [262]. https://doi.org/10.1186/s12887-018-1215-7