Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation

Nikki A. H. A. Pluymaekers; Elton A. M. P. Dudink; Justin G. L. M. Luermans; Joan G. Meeder; Timo Lenderink; Jos Widdershoven; Jeroen J. J. Bucx; Michiel Rienstra; Otto Kamp; Jurren M. Van Opstal; Marco Alings; Anton Oomen; Charles J. Kirchhof; Vincent F. Van Dijk; Hemanth Ramanna; Anho Liem; Lukas R. Dekker; Brigitte A. B. Essers; Jan G. P. Tijssen; Isabelle C. Van Gelder; Harry J. G. M. Crijns; RACE 7 ACWAS Investigators

doi:10.1056/NEJMoa1900353

Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation

Nikki A. H. A. Pluymaekers, Elton A. M. P. Dudink, Justin G. L. M. Luermans, Joan G. Meeder, Timo Lenderink, Jos Widdershoven, Jeroen J. J. Bucx, Michiel Rienstra, Otto Kamp, Jurren M. Van Opstal, Marco Alings, Anton Oomen, Charles J. Kirchhof, Vincent F. Van Dijk, Hemanth Ramanna, Anho Liem, Lukas R. Dekker, Brigitte A. B. Essers, Jan G. P. Tijssen, Isabelle C. Van GelderHarry J. G. M. Crijns^*, RACE 7 ACWAS Investigators

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

88 Citations (Web of Science)

Abstract

Background Patients with recent-onset atrial fibrillation commonly undergo immediate restoration of sinus rhythm by pharmacologic or electrical cardioversion. However, whether immediate restoration of sinus rhythm is necessary is not known, since atrial fibrillation often terminates spontaneously. Methods In a multicenter, randomized, open-label, noninferiority trial, we randomly assigned patients with hemodynamically stable, recent-onset (

Original language	English
Pages (from-to)	1499-1508
Number of pages	10
Journal	New England Journal of Medicine
Volume	380
Issue number	16
DOIs	https://doi.org/10.1056/NEJMoa1900353
Publication status	Published - 18 Apr 2019

Keywords

ABLATION
ANTICOAGULATION
CATHETER
DESIGN
ECHOCARDIOGRAPHY
GUIDELINES
MANAGEMENT
SPONTANEOUS CONVERSION
STROKE
TEMPORAL RELATIONSHIP
DEVICE

Access to Document

10.1056/NEJMoa1900353

Cite this

Pluymaekers, N. A. H. A., Dudink, E. A. M. P., Luermans, J. G. L. M., Meeder, J. G., Lenderink, T., Widdershoven, J., Bucx, J. J. J., Rienstra, M., Kamp, O., Van Opstal, J. M., Alings, M., Oomen, A., Kirchhof, C. J., Van Dijk, V. F., Ramanna, H., Liem, A., Dekker, L. R., Essers, B. A. B., Tijssen, J. G. P., ... RACE 7 ACWAS Investigators (2019). Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation. New England Journal of Medicine, 380(16), 1499-1508. https://doi.org/10.1056/NEJMoa1900353

@article{d3ec1bc4ba1c4b8ebe14a4435c2a2a20,

title = "Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation",

abstract = "Background Patients with recent-onset atrial fibrillation commonly undergo immediate restoration of sinus rhythm by pharmacologic or electrical cardioversion. However, whether immediate restoration of sinus rhythm is necessary is not known, since atrial fibrillation often terminates spontaneously. Methods In a multicenter, randomized, open-label, noninferiority trial, we randomly assigned patients with hemodynamically stable, recent-onset (",

keywords = "ABLATION, ANTICOAGULATION, CATHETER, DESIGN, ECHOCARDIOGRAPHY, GUIDELINES, MANAGEMENT, SPONTANEOUS CONVERSION, STROKE, TEMPORAL RELATIONSHIP, DEVICE",

author = "Pluymaekers, {Nikki A. H. A.} and Dudink, {Elton A. M. P.} and Luermans, {Justin G. L. M.} and Meeder, {Joan G.} and Timo Lenderink and Jos Widdershoven and Bucx, {Jeroen J. J.} and Michiel Rienstra and Otto Kamp and {Van Opstal}, {Jurren M.} and Marco Alings and Anton Oomen and Kirchhof, {Charles J.} and {Van Dijk}, {Vincent F.} and Hemanth Ramanna and Anho Liem and Dekker, {Lukas R.} and Essers, {Brigitte A. B.} and Tijssen, {Jan G. P.} and {Van Gelder}, {Isabelle C.} and Crijns, {Harry J. G. M.} and {RACE 7 ACWAS Investigators}",

year = "2019",

month = apr,

day = "18",

doi = "10.1056/NEJMoa1900353",

language = "English",

volume = "380",

pages = "1499--1508",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "MASSACHUSETTS MEDICAL SOCIETY",

number = "16",

}

Pluymaekers, NAHA , Dudink, EAMP , Luermans, JGLM, Meeder, JG, Lenderink, T, Widdershoven, J, Bucx, JJJ, Rienstra, M, Kamp, O, Van Opstal, JM, Alings, M, Oomen, A, Kirchhof, CJ, Van Dijk, VF, Ramanna, H, Liem, A, Dekker, LR, Essers, BAB, Tijssen, JGP, Van Gelder, IC, Crijns, HJGM & RACE 7 ACWAS Investigators 2019, 'Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation', New England Journal of Medicine, vol. 380, no. 16, pp. 1499-1508. https://doi.org/10.1056/NEJMoa1900353

TY - JOUR

T1 - Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation

AU - Pluymaekers, Nikki A. H. A.

AU - Dudink, Elton A. M. P.

AU - Luermans, Justin G. L. M.

AU - Meeder, Joan G.

AU - Lenderink, Timo

AU - Widdershoven, Jos

AU - Bucx, Jeroen J. J.

AU - Rienstra, Michiel

AU - Kamp, Otto

AU - Van Opstal, Jurren M.

AU - Alings, Marco

AU - Oomen, Anton

AU - Kirchhof, Charles J.

AU - Van Dijk, Vincent F.

AU - Ramanna, Hemanth

AU - Liem, Anho

AU - Dekker, Lukas R.

AU - Essers, Brigitte A. B.

AU - Tijssen, Jan G. P.

AU - Van Gelder, Isabelle C.

AU - Crijns, Harry J. G. M.

AU - RACE 7 ACWAS Investigators

PY - 2019/4/18

Y1 - 2019/4/18

N2 - Background Patients with recent-onset atrial fibrillation commonly undergo immediate restoration of sinus rhythm by pharmacologic or electrical cardioversion. However, whether immediate restoration of sinus rhythm is necessary is not known, since atrial fibrillation often terminates spontaneously. Methods In a multicenter, randomized, open-label, noninferiority trial, we randomly assigned patients with hemodynamically stable, recent-onset (

AB - Background Patients with recent-onset atrial fibrillation commonly undergo immediate restoration of sinus rhythm by pharmacologic or electrical cardioversion. However, whether immediate restoration of sinus rhythm is necessary is not known, since atrial fibrillation often terminates spontaneously. Methods In a multicenter, randomized, open-label, noninferiority trial, we randomly assigned patients with hemodynamically stable, recent-onset (

KW - ABLATION

KW - ANTICOAGULATION

KW - CATHETER

KW - DESIGN

KW - ECHOCARDIOGRAPHY

KW - GUIDELINES

KW - MANAGEMENT

KW - SPONTANEOUS CONVERSION

KW - STROKE

KW - TEMPORAL RELATIONSHIP

KW - DEVICE

U2 - 10.1056/NEJMoa1900353

DO - 10.1056/NEJMoa1900353

M3 - Article

VL - 380

SP - 1499

EP - 1508

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 16

ER -