Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation

Nikki A. H. A. Pluymaekers, Elton A. M. P. Dudink, Justin G. L. M. Luermans, Joan G. Meeder, Timo Lenderink, Jos Widdershoven, Jeroen J. J. Bucx, Michiel Rienstra, Otto Kamp, Jurren M. Van Opstal, Marco Alings, Anton Oomen, Charles J. Kirchhof, Vincent F. Van Dijk, Hemanth Ramanna, Anho Liem, Lukas R. Dekker, Brigitte A. B. Essers, Jan G. P. Tijssen, Isabelle C. Van GelderHarry J. G. M. Crijns*, RACE 7 ACWAS Investigators

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

88 Citations (Web of Science)

Abstract

Background Patients with recent-onset atrial fibrillation commonly undergo immediate restoration of sinus rhythm by pharmacologic or electrical cardioversion. However, whether immediate restoration of sinus rhythm is necessary is not known, since atrial fibrillation often terminates spontaneously. Methods In a multicenter, randomized, open-label, noninferiority trial, we randomly assigned patients with hemodynamically stable, recent-onset (

Original languageEnglish
Pages (from-to)1499-1508
Number of pages10
JournalNew England Journal of Medicine
Volume380
Issue number16
DOIs
Publication statusPublished - 18 Apr 2019

Keywords

  • ABLATION
  • ANTICOAGULATION
  • CATHETER
  • DESIGN
  • ECHOCARDIOGRAPHY
  • GUIDELINES
  • MANAGEMENT
  • SPONTANEOUS CONVERSION
  • STROKE
  • TEMPORAL RELATIONSHIP
  • DEVICE

Cite this