Early effect of intra-arterial treatment in ischemic stroke on aphasia recovery in MR CLEAN

  • Yvette S. Crijnen
  • , Femke Nouwens
  • , Lonneke M. L. de Lau
  • , Evy G. Visch-Brink
  • , Mieke W. M. E. van de Sandt-Koenderman
  • , Olvert A. Berkhemer
  • , Puck S. S. Fransen
  • , Debbie Beumer
  • , Lucie A. van den Berg
  • , Hester F. Lingsma
  • , Yvo B. W. E. M. Roos
  • , Aad van der Lugt
  • , Robert J. van Oostenbrugge
  • , Wim H. van Zwam
  • , Charles B. L. M. Majoie
  • , Diederik W. J. Dippel*
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objective:To investigate the effect of intra-arterial treatment (IAT) on early recovery from aphasia in acute ischemic stroke. We hypothesized that the early effect of IAT on aphasia is smaller than the effect on motor deficits.Methods:We included patients with aphasia from the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN), in which 500 patients with a proximal anterior circulation stroke were randomized to usual care plus IAT (
Original languageEnglish
Pages (from-to)2049-2055
Number of pages7
JournalNeurology
Volume86
Issue number22
DOIs
Publication statusPublished - 31 May 2016

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