Early effect of intra-arterial treatment in ischemic stroke on aphasia recovery in MR CLEAN

Yvette S. Crijnen, Femke Nouwens, Lonneke M. L. de Lau, Evy G. Visch-Brink, Mieke W. M. E. van de Sandt-Koenderman, Olvert A. Berkhemer, Puck S. S. Fransen, Debbie Beumer, Lucie A. van den Berg, Hester F. Lingsma, Yvo B. W. E. M. Roos, Aad van der Lugt, Robert J. van Oostenbrugge, Wim H. van Zwam, Charles B. L. M. Majoie, Diederik W. J. Dippel*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objective:To investigate the effect of intra-arterial treatment (IAT) on early recovery from aphasia in acute ischemic stroke. We hypothesized that the early effect of IAT on aphasia is smaller than the effect on motor deficits.Methods:We included patients with aphasia from the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN), in which 500 patients with a proximal anterior circulation stroke were randomized to usual care plus IAT (
Original languageEnglish
Pages (from-to)2049-2055
JournalNeurology
Volume86
Issue number22
DOIs
Publication statusPublished - 31 May 2016

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