DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds

Diana M. Hendrickx*, Terezinha Souza, Danyel G. J. Jennen, Jos C. S. Kleinjans

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Web of Science)
Original languageEnglish
Pages (from-to)2343-2352
Number of pages10
JournalArchives of Toxicology
Volume91
Issue number6
DOIs
Publication statusPublished - Jun 2017

Keywords

  • Time series
  • Dose-response
  • Gene regulatory network inference
  • Mode of action
  • Molecular initiating event
  • Key event
  • INDUCED LIVER-INJURY
  • GENE-EXPRESSION PROFILES
  • FACTOR-KAPPA-B
  • ACETAMINOPHEN HEPATOTOXICITY
  • DIFFERENTIAL EXPRESSION
  • OUTCOME PATHWAYS
  • RISK-ASSESSMENT
  • IN-VITRO
  • CANCER
  • KNOWLEDGE

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