Drug-induced interstitial lung disease: role of pharmacogenetics in predicting cytotoxic mechanisms and risks of side effects

Naomi T. Jessurun; Marjolein Drent; Eugene P. van Puijenbroek; Otto Bekers; Petal A. Wijnen; Aalt Bast

doi:10.1097/MCP.0000000000000590

Drug-induced interstitial lung disease: role of pharmacogenetics in predicting cytotoxic mechanisms and risks of side effects

Naomi T. Jessurun, Marjolein Drent, Eugene P. van Puijenbroek, Otto Bekers, Petal A. Wijnen, Aalt Bast^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Original language	English
Pages (from-to)	468-477
Number of pages	10
Journal	Current Opinion in Pulmonary Medicine
Volume	25
Issue number	5
DOIs	https://doi.org/10.1097/MCP.0000000000000590
Publication status	Published - Sep 2019

Keywords

adverse drug reactions
cytochrome P450
cytotoxic mechanisms
drug metabolizing enzymes
drug-induced pneumonitis
glucose-6-phosphate dehydrogenase
polymorphisms
thiopurine S-methyltransferase
xenobiotics
THIOPURINE METHYLTRANSFERASE
GENETIC-POLYMORPHISM
ACETAMINOPHEN
METABOLISM
INJURY
BIOACTIVATION
4-IPOMEANOL
OXIDATION
TOXICITY
PROTEINS

Access to Document

10.1097/MCP.0000000000000590

Cite this

@article{b388450cc43947d69bf7b6638ac6707e,

title = "Drug-induced interstitial lung disease: role of pharmacogenetics in predicting cytotoxic mechanisms and risks of side effects",

keywords = "adverse drug reactions, cytochrome P450, cytotoxic mechanisms, drug metabolizing enzymes, drug-induced pneumonitis, glucose-6-phosphate dehydrogenase, polymorphisms, thiopurine S-methyltransferase, xenobiotics, THIOPURINE METHYLTRANSFERASE, GENETIC-POLYMORPHISM, ACETAMINOPHEN, METABOLISM, INJURY, BIOACTIVATION, 4-IPOMEANOL, OXIDATION, TOXICITY, PROTEINS",

author = "Jessurun, {Naomi T.} and Marjolein Drent and {van Puijenbroek}, {Eugene P.} and Otto Bekers and Wijnen, {Petal A.} and Aalt Bast",

year = "2019",

month = sep,

doi = "10.1097/MCP.0000000000000590",

language = "English",

volume = "25",

pages = "468--477",

journal = "Current Opinion in Pulmonary Medicine",

issn = "1070-5287",

publisher = "LIPPINCOTT WILLIAMS & WILKINS",

number = "5",

}

Drug-induced interstitial lung disease : role of pharmacogenetics in predicting cytotoxic mechanisms and risks of side effects. / Jessurun, Naomi T.; Drent, Marjolein; van Puijenbroek, Eugene P.; Bekers, Otto ; Wijnen, Petal A.; Bast, Aalt.

In: Current Opinion in Pulmonary Medicine, Vol. 25, No. 5, 09.2019, p. 468-477.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Drug-induced interstitial lung disease

T2 - role of pharmacogenetics in predicting cytotoxic mechanisms and risks of side effects

AU - Jessurun, Naomi T.

AU - Drent, Marjolein

AU - van Puijenbroek, Eugene P.

AU - Bekers, Otto

AU - Wijnen, Petal A.

AU - Bast, Aalt

PY - 2019/9

Y1 - 2019/9

KW - adverse drug reactions

KW - cytochrome P450

KW - cytotoxic mechanisms

KW - drug metabolizing enzymes

KW - drug-induced pneumonitis

KW - glucose-6-phosphate dehydrogenase

KW - polymorphisms

KW - thiopurine S-methyltransferase

KW - xenobiotics

KW - THIOPURINE METHYLTRANSFERASE

KW - GENETIC-POLYMORPHISM

KW - ACETAMINOPHEN

KW - METABOLISM

KW - INJURY

KW - BIOACTIVATION

KW - 4-IPOMEANOL

KW - OXIDATION

KW - TOXICITY

KW - PROTEINS

U2 - 10.1097/MCP.0000000000000590

DO - 10.1097/MCP.0000000000000590

M3 - Review article

C2 - 31365381

VL - 25

SP - 468

EP - 477

JO - Current Opinion in Pulmonary Medicine

JF - Current Opinion in Pulmonary Medicine

SN - 1070-5287

IS - 5

ER -