Downregulation of the FTO m(6)A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors

Jana Jeschke, Evelyne Collignon, Clemence Al Wardi, Mohammad Krayem, Martin Bizet, Yan Jia, Soizic Garaud, Zena Wimana, Emilie Calonne, Bouchra Hassabi, Renato Morandini, Rachel Deplus, Pascale Putmans, Gaurav Dube, Nitesh Kumar Singh, Alexander Koch, Kateryna Shostak, Lara Rizzotto, Robert L. Ross, Christine DesmedtYacine Bareche, Francoise Rothe, Jacqueline Lehmann-Che, Martine Duterque-Coquillaud, Xavier Leroy, Gerben Menschaert, Luis Teixeira, Mingzhou Guo, Patrick A. Limbach, Pierre Close, Alain Chariot, Eleonora Leucci, Ghanem Ghanem, Bi-Feng Yuan, Karen Willard-Gallo, Christos Sotiriou, Jean-Christophe Marine, Francois Fuks*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Web of Science)
Original languageEnglish
Pages (from-to)611-+
Number of pages30
JournalNature Cancer
Volume2
Issue number6
DOIs
Publication statusPublished - Jun 2021

Keywords

  • BREAST-CANCER
  • MESSENGER-RNAS
  • METHYLATION
  • EXPRESSION
  • ACTIVATION
  • REVEALS
  • MASS
  • N6-METHYLADENOSINE
  • DIFFERENTIATION
  • POLYADENYLATION

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