Disturbed cognitive functions after nasal provocation in patients with seasonal allergic rhinitis

I. Hartgerink-Lutgens, A. Vermeeren, E.F.P.M. Vuurman, B. Kremer

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Abstract

BACKGROUND: Allergic rhinitis (AR) reduces quality of life as a result of impaired psychological well-being and perceived impaired cognitive functioning. Few studies have measured cognitive functions objectively and it remains uncertain whether AR leads to an objective reduction in cognitive functions. OBJECTIVE: The present study investigated whether AR is associated with a decrement in several aspects of cognitive functioning. Furthermore, the study investigated whether AR patients invest more 'mental effort' in order to achieve the same cognitive performances as healthy controls. METHODS: Twenty five patients with seasonal allergic rhinitis (SAR) and 26 healthy controls, matched for age, education and sex, were tested on a battery of time-demanding and strenuous objective cognitive tests and subjective questionnaires, both before and after nasal provocation (NP). The cognitive functions assessed were sustained attention, short- and long-term memory and speed of information processing. Mental effort was assessed using visual rating scales. RESULTS: Sustained but not short cognitive performance was impaired in patients after NP. Patients showed an increased effort on short cognitive tests. CONCLUSION: SAR patients suffer from cognitive performance decrements that can be compensated by additional mental effort for short tasks only.
Original languageEnglish
Pages (from-to)500-508
JournalClinical and Experimental Allergy
Volume39
Issue number4
DOIs
Publication statusPublished - 1 Jan 2009

Cite this

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title = "Disturbed cognitive functions after nasal provocation in patients with seasonal allergic rhinitis",
abstract = "BACKGROUND: Allergic rhinitis (AR) reduces quality of life as a result of impaired psychological well-being and perceived impaired cognitive functioning. Few studies have measured cognitive functions objectively and it remains uncertain whether AR leads to an objective reduction in cognitive functions. OBJECTIVE: The present study investigated whether AR is associated with a decrement in several aspects of cognitive functioning. Furthermore, the study investigated whether AR patients invest more 'mental effort' in order to achieve the same cognitive performances as healthy controls. METHODS: Twenty five patients with seasonal allergic rhinitis (SAR) and 26 healthy controls, matched for age, education and sex, were tested on a battery of time-demanding and strenuous objective cognitive tests and subjective questionnaires, both before and after nasal provocation (NP). The cognitive functions assessed were sustained attention, short- and long-term memory and speed of information processing. Mental effort was assessed using visual rating scales. RESULTS: Sustained but not short cognitive performance was impaired in patients after NP. Patients showed an increased effort on short cognitive tests. CONCLUSION: SAR patients suffer from cognitive performance decrements that can be compensated by additional mental effort for short tasks only.",
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Disturbed cognitive functions after nasal provocation in patients with seasonal allergic rhinitis. / Hartgerink-Lutgens, I.; Vermeeren, A.; Vuurman, E.F.P.M.; Kremer, B.

In: Clinical and Experimental Allergy, Vol. 39, No. 4, 01.01.2009, p. 500-508.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

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AU - Hartgerink-Lutgens, I.

AU - Vermeeren, A.

AU - Vuurman, E.F.P.M.

AU - Kremer, B.

PY - 2009/1/1

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N2 - BACKGROUND: Allergic rhinitis (AR) reduces quality of life as a result of impaired psychological well-being and perceived impaired cognitive functioning. Few studies have measured cognitive functions objectively and it remains uncertain whether AR leads to an objective reduction in cognitive functions. OBJECTIVE: The present study investigated whether AR is associated with a decrement in several aspects of cognitive functioning. Furthermore, the study investigated whether AR patients invest more 'mental effort' in order to achieve the same cognitive performances as healthy controls. METHODS: Twenty five patients with seasonal allergic rhinitis (SAR) and 26 healthy controls, matched for age, education and sex, were tested on a battery of time-demanding and strenuous objective cognitive tests and subjective questionnaires, both before and after nasal provocation (NP). The cognitive functions assessed were sustained attention, short- and long-term memory and speed of information processing. Mental effort was assessed using visual rating scales. RESULTS: Sustained but not short cognitive performance was impaired in patients after NP. Patients showed an increased effort on short cognitive tests. CONCLUSION: SAR patients suffer from cognitive performance decrements that can be compensated by additional mental effort for short tasks only.

AB - BACKGROUND: Allergic rhinitis (AR) reduces quality of life as a result of impaired psychological well-being and perceived impaired cognitive functioning. Few studies have measured cognitive functions objectively and it remains uncertain whether AR leads to an objective reduction in cognitive functions. OBJECTIVE: The present study investigated whether AR is associated with a decrement in several aspects of cognitive functioning. Furthermore, the study investigated whether AR patients invest more 'mental effort' in order to achieve the same cognitive performances as healthy controls. METHODS: Twenty five patients with seasonal allergic rhinitis (SAR) and 26 healthy controls, matched for age, education and sex, were tested on a battery of time-demanding and strenuous objective cognitive tests and subjective questionnaires, both before and after nasal provocation (NP). The cognitive functions assessed were sustained attention, short- and long-term memory and speed of information processing. Mental effort was assessed using visual rating scales. RESULTS: Sustained but not short cognitive performance was impaired in patients after NP. Patients showed an increased effort on short cognitive tests. CONCLUSION: SAR patients suffer from cognitive performance decrements that can be compensated by additional mental effort for short tasks only.

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