TY - JOUR
T1 - Distribution of dopaminergic cell bodies in the median raphe nucleus of the rat brain
AU - Jahanshahi, Ali
AU - Steinbusch, Harry W. M.
AU - Temel, Yasin
PY - 2013/11
Y1 - 2013/11
N2 - An increasing amount of data suggests that a dysfunction in dopamine (DA) neurotransmission is involved in the pathophysiology of various neurological and psychiatric disorders. With this in mind, the distribution and connectivity of the dopaminergic system in the rat brain has been studied extensively. So far, little is known about the distribution of DA containing neurons in the median raphe nucleus (MnR). This nucleus is mainly defined by a large population of serotonin containing neurons. Using quantitative immunohistochemistry, we observed the presence of a small number of DA containing neurons in the rat MnR, which was in contrast to a previous report.
AB - An increasing amount of data suggests that a dysfunction in dopamine (DA) neurotransmission is involved in the pathophysiology of various neurological and psychiatric disorders. With this in mind, the distribution and connectivity of the dopaminergic system in the rat brain has been studied extensively. So far, little is known about the distribution of DA containing neurons in the median raphe nucleus (MnR). This nucleus is mainly defined by a large population of serotonin containing neurons. Using quantitative immunohistochemistry, we observed the presence of a small number of DA containing neurons in the rat MnR, which was in contrast to a previous report.
KW - Median raphe nucleus
KW - Dopamine
KW - Tyrosine Hydroxylase
U2 - 10.1016/j.jchemneu.2013.09.002
DO - 10.1016/j.jchemneu.2013.09.002
M3 - Article
C2 - 24140412
SN - 0891-0618
VL - 53
SP - 60
EP - 63
JO - Journal of Chemical Neuroanatomy
JF - Journal of Chemical Neuroanatomy
ER -