Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation

Niall Mortimer; Tatjana Ganster; Aet O'Leary; Sandy Popp; Florian Freudenberg; Andreas Reif; Maria Soler Artigas; Marta Ribases; Josep Antoni Ramos-Quiroga; Klaus-Peter Lesch; Olga Rivero

doi:10.1016/j.neuropharm.2019.02.039

Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation

Niall Mortimer, Tatjana Ganster, Aet O'Leary, Sandy Popp, Florian Freudenberg, Andreas Reif, Maria Soler Artigas, Marta Ribases, Josep Antoni Ramos-Quiroga, Klaus-Peter Lesch, Olga Rivero^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	107557
Number of pages	17
Journal	Neuropharmacology
Volume	156
DOIs	https://doi.org/10.1016/j.neuropharm.2019.02.039
Publication status	Published - 15 Sep 2019

Keywords

Adhesion G protein-coupled receptor L3 (ADGRL3)
Latrophilin
Latrophilin 3 (LPHN3)
Attention-deficit/hyperactivity disorder (ADHD)
Prefrontal cortex
Striatum
Hippocampus
Mouse model
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER
GENOME-WIDE ASSOCIATION
PREFRONTAL CORTEX
ANIMAL-MODEL
AMYGDALA MORPHOLOGY
LPHN3
GAIT
METHYLPHENIDATE
CHILDREN
NEUROTRANSMISSION

Access to Document

10.1016/j.neuropharm.2019.02.039

Cite this

Mortimer, N., Ganster, T., O'Leary, A., Popp, S., Freudenberg, F., Reif, A., Soler Artigas, M., Ribases, M., Antoni Ramos-Quiroga, J., Lesch, K-P., & Rivero, O. (2019). Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation. Neuropharmacology, 156, [107557]. https://doi.org/10.1016/j.neuropharm.2019.02.039

Mortimer, Niall ; Ganster, Tatjana ; O'Leary, Aet ; Popp, Sandy ; Freudenberg, Florian ; Reif, Andreas ; Soler Artigas, Maria ; Ribases, Marta ; Antoni Ramos-Quiroga, Josep ; Lesch, Klaus-Peter ; Rivero, Olga. / Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3 : Evidence for dopamine transporter dysregulation. In: Neuropharmacology. 2019 ; Vol. 156.

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title = "Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation",

keywords = "Adhesion G protein-coupled receptor L3 (ADGRL3), Latrophilin, Latrophilin 3 (LPHN3), Attention-deficit/hyperactivity disorder (ADHD), Prefrontal cortex, Striatum, Hippocampus, Mouse model, ATTENTION-DEFICIT/HYPERACTIVITY DISORDER, GENOME-WIDE ASSOCIATION, PREFRONTAL CORTEX, ANIMAL-MODEL, AMYGDALA MORPHOLOGY, LPHN3, GAIT, METHYLPHENIDATE, CHILDREN, NEUROTRANSMISSION",

author = "Niall Mortimer and Tatjana Ganster and Aet O'Leary and Sandy Popp and Florian Freudenberg and Andreas Reif and {Soler Artigas}, Maria and Marta Ribases and {Antoni Ramos-Quiroga}, Josep and Klaus-Peter Lesch and Olga Rivero",

year = "2019",

month = sep,

day = "15",

doi = "10.1016/j.neuropharm.2019.02.039",

language = "English",

volume = "156",

journal = "Neuropharmacology",

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Mortimer, N, Ganster, T, O'Leary, A, Popp, S, Freudenberg, F, Reif, A, Soler Artigas, M, Ribases, M, Antoni Ramos-Quiroga, J, Lesch, K-P & Rivero, O 2019, 'Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation', Neuropharmacology, vol. 156, 107557. https://doi.org/10.1016/j.neuropharm.2019.02.039

Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3 : Evidence for dopamine transporter dysregulation. / Mortimer, Niall; Ganster, Tatjana; O'Leary, Aet; Popp, Sandy; Freudenberg, Florian; Reif, Andreas; Soler Artigas, Maria; Ribases, Marta; Antoni Ramos-Quiroga, Josep; Lesch, Klaus-Peter; Rivero, Olga.

In: Neuropharmacology, Vol. 156, 107557, 15.09.2019.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3

T2 - Evidence for dopamine transporter dysregulation

AU - Mortimer, Niall

AU - Ganster, Tatjana

AU - O'Leary, Aet

AU - Popp, Sandy

AU - Freudenberg, Florian

AU - Reif, Andreas

AU - Soler Artigas, Maria

AU - Ribases, Marta

AU - Antoni Ramos-Quiroga, Josep

AU - Lesch, Klaus-Peter

AU - Rivero, Olga

PY - 2019/9/15

Y1 - 2019/9/15

KW - Adhesion G protein-coupled receptor L3 (ADGRL3)

KW - Latrophilin

KW - Latrophilin 3 (LPHN3)

KW - Attention-deficit/hyperactivity disorder (ADHD)

KW - Prefrontal cortex

KW - Striatum

KW - Hippocampus

KW - Mouse model

KW - ATTENTION-DEFICIT/HYPERACTIVITY DISORDER

KW - GENOME-WIDE ASSOCIATION

KW - PREFRONTAL CORTEX

KW - ANIMAL-MODEL

KW - AMYGDALA MORPHOLOGY

KW - LPHN3

KW - GAIT

KW - METHYLPHENIDATE

KW - CHILDREN

KW - NEUROTRANSMISSION

U2 - 10.1016/j.neuropharm.2019.02.039

DO - 10.1016/j.neuropharm.2019.02.039

M3 - Article

C2 - 30849401

VL - 156

JO - Neuropharmacology

JF - Neuropharmacology

SN - 0028-3908

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ER -