Discovery and assessment of water soluble coumarins as inhibitors of the coagulation contact pathway

Charlotte Bouckaert; Shu Zhu; Jose W. P. Govers-Riemslag; Maxime Depoorter; Scott L. Diamond; Lionel Pochet

doi:10.1016/j.thromres.2017.07.015

Discovery and assessment of water soluble coumarins as inhibitors of the coagulation contact pathway

Charlotte Bouckaert, Shu Zhu, Jose W. P. Govers-Riemslag, Maxime Depoorter, Scott L. Diamond, Lionel Pochet^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	126-133
Number of pages	8
Journal	Thrombosis Research
Volume	157
DOIs	https://doi.org/10.1016/j.thromres.2017.07.015
Publication status	Published - Sep 2017

Keywords

FXII
FXIIa
Coumarin
Inhibitor
Factor XII
Contact system
CORN TRYPSIN-INHIBITOR
MECHANISM-BASED INHIBITORS
FACTOR-XII
THROMBUS FORMATION
IN-VIVO
CATHETER THROMBOSIS
INTRINSIC PATHWAY
FXIIA INHIBITORS
ACTIVATION
BLOOD

Access to Document

10.1016/j.thromres.2017.07.015

Cite this

Bouckaert, C., Zhu, S., Govers-Riemslag, J. W. P., Depoorter, M., Diamond, S. L., & Pochet, L. (2017). Discovery and assessment of water soluble coumarins as inhibitors of the coagulation contact pathway. Thrombosis Research, 157, 126-133. https://doi.org/10.1016/j.thromres.2017.07.015

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title = "Discovery and assessment of water soluble coumarins as inhibitors of the coagulation contact pathway",

keywords = "FXII, FXIIa, Coumarin, Inhibitor, Factor XII, Contact system, CORN TRYPSIN-INHIBITOR, MECHANISM-BASED INHIBITORS, FACTOR-XII, THROMBUS FORMATION, IN-VIVO, CATHETER THROMBOSIS, INTRINSIC PATHWAY, FXIIA INHIBITORS, ACTIVATION, BLOOD",

author = "Charlotte Bouckaert and Shu Zhu and Govers-Riemslag, {Jose W. P.} and Maxime Depoorter and Diamond, {Scott L.} and Lionel Pochet",

year = "2017",

month = sep,

doi = "10.1016/j.thromres.2017.07.015",

language = "English",

volume = "157",

pages = "126--133",

journal = "Thrombosis Research",

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TY - JOUR

T1 - Discovery and assessment of water soluble coumarins as inhibitors of the coagulation contact pathway

AU - Bouckaert, Charlotte

AU - Zhu, Shu

AU - Govers-Riemslag, Jose W. P.

AU - Depoorter, Maxime

AU - Diamond, Scott L.

AU - Pochet, Lionel

PY - 2017/9

Y1 - 2017/9

KW - FXII

KW - FXIIa

KW - Coumarin

KW - Inhibitor

KW - Factor XII

KW - Contact system

KW - CORN TRYPSIN-INHIBITOR

KW - MECHANISM-BASED INHIBITORS

KW - FACTOR-XII

KW - THROMBUS FORMATION

KW - IN-VIVO

KW - CATHETER THROMBOSIS

KW - INTRINSIC PATHWAY

KW - FXIIA INHIBITORS

KW - ACTIVATION

KW - BLOOD

U2 - 10.1016/j.thromres.2017.07.015

DO - 10.1016/j.thromres.2017.07.015

M3 - Article

VL - 157

SP - 126

EP - 133

JO - Thrombosis Research

JF - Thrombosis Research

SN - 0049-3848

ER -