Directed Assembly and Development of Material-Free Tissues with Complex Architectures

Erik Vrij; Jeroen Rouwkema; Vanessa LaPointe; Clemens van Blitterswijk; Roman Truckenmuller; Nicolas Rivron

doi:10.1002/adma.201505723

Directed Assembly and Development of Material-Free Tissues with Complex Architectures

Erik Vrij, Jeroen Rouwkema, Vanessa LaPointe, Clemens van Blitterswijk, Roman Truckenmuller, Nicolas Rivron^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis.

Original language	English
Pages (from-to)	4032-4039
Journal	Advanced Materials
Volume	28
Issue number	21
DOIs	https://doi.org/10.1002/adma.201505723
Publication status	Published - 1 Jun 2016

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title = "Directed Assembly and Development of Material-Free Tissues with Complex Architectures",

abstract = "Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis.",

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AU - Rouwkema, Jeroen

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AU - Truckenmuller, Roman

AU - Rivron, Nicolas

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AB - Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis.

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DO - 10.1002/adma.201505723

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JO - Advanced Materials

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Directed Assembly and Development of Material-Free Tissues with Complex Architectures

Abstract

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