Directed Assembly and Development of Material-Free Tissues with Complex Architectures

Erik Vrij, Jeroen Rouwkema, Vanessa LaPointe, Clemens van Blitterswijk, Roman Truckenmuller, Nicolas Rivron*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis.
Original languageEnglish
Pages (from-to)4032-4039
JournalAdvanced Materials
Volume28
Issue number21
DOIs
Publication statusPublished - 1 Jun 2016

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