Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice

Veronica Valero-Esquitino; Kristin Lucht; Pawel Namsolleck; Florianne Monnet-Tschudi; Tobias Stubbe; Franziska Lucht; Meng Liu; Friederike Ebner; Christine Brandt; Leon A. Danyel; Daniel C. Villela; Ludovit Paulis; Christa Thoene-Reineke; Bjoern Dahloef; Anders Hallberg; Thomas Unger; Colin Sumners; U. Muscha Steckelings

doi:10.1042/CS20130601

Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice

Veronica Valero-Esquitino, Kristin Lucht, Pawel Namsolleck, Florianne Monnet-Tschudi, Tobias Stubbe, Franziska Lucht, Meng Liu, Friederike Ebner, Christine Brandt, Leon A. Danyel, Daniel C. Villela, Ludovit Paulis, Christa Thoene-Reineke, Bjoern Dahloef, Anders Hallberg, Thomas Unger, Colin Sumners, U. Muscha Steckelings^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	95-109
Journal	Clinical Science
Volume	128
Issue number	2
DOIs	https://doi.org/10.1042/CS20130601
Publication status	Published - Jan 2015

Keywords

angiotensin type 2 receptor (AT(2)R)
experimental autoimmune encephalomyelitis
multiple sclerosis
neuroinflammation
neuroprotection
new therapies

Access to Document

10.1042/CS20130601

Cite this

Valero-Esquitino, V., Lucht, K., Namsolleck, P., Monnet-Tschudi, F., Stubbe, T., Lucht, F., Liu, M., Ebner, F., Brandt, C., Danyel, L. A., Villela, D. C., Paulis, L., Thoene-Reineke, C., Dahloef, B., Hallberg, A., Unger, T., Sumners, C., & Steckelings, U. M. (2015). Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice. Clinical Science, 128(2), 95-109. https://doi.org/10.1042/CS20130601

Valero-Esquitino, Veronica ; Lucht, Kristin ; Namsolleck, Pawel ; Monnet-Tschudi, Florianne ; Stubbe, Tobias ; Lucht, Franziska ; Liu, Meng ; Ebner, Friederike ; Brandt, Christine ; Danyel, Leon A. ; Villela, Daniel C. ; Paulis, Ludovit ; Thoene-Reineke, Christa ; Dahloef, Bjoern ; Hallberg, Anders ; Unger, Thomas ; Sumners, Colin ; Steckelings, U. Muscha. / Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice. In: Clinical Science. 2015 ; Vol. 128, No. 2. pp. 95-109.

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title = "Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice",

keywords = "angiotensin type 2 receptor (AT(2)R), experimental autoimmune encephalomyelitis, multiple sclerosis, neuroinflammation, neuroprotection, new therapies",

author = "Veronica Valero-Esquitino and Kristin Lucht and Pawel Namsolleck and Florianne Monnet-Tschudi and Tobias Stubbe and Franziska Lucht and Meng Liu and Friederike Ebner and Christine Brandt and Danyel, {Leon A.} and Villela, {Daniel C.} and Ludovit Paulis and Christa Thoene-Reineke and Bjoern Dahloef and Anders Hallberg and Thomas Unger and Colin Sumners and Steckelings, {U. Muscha}",

year = "2015",

month = jan,

doi = "10.1042/CS20130601",

language = "English",

volume = "128",

pages = "95--109",

journal = "Clinical Science",

issn = "0143-5221",

publisher = "Portland Press Ltd.",

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Valero-Esquitino, V, Lucht, K, Namsolleck, P, Monnet-Tschudi, F, Stubbe, T, Lucht, F, Liu, M, Ebner, F, Brandt, C, Danyel, LA, Villela, DC, Paulis, L, Thoene-Reineke, C, Dahloef, B, Hallberg, A, Unger, T, Sumners, C & Steckelings, UM 2015, 'Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice', Clinical Science, vol. 128, no. 2, pp. 95-109. https://doi.org/10.1042/CS20130601

Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice. / Valero-Esquitino, Veronica; Lucht, Kristin; Namsolleck, Pawel; Monnet-Tschudi, Florianne; Stubbe, Tobias; Lucht, Franziska; Liu, Meng; Ebner, Friederike; Brandt, Christine; Danyel, Leon A.; Villela, Daniel C.; Paulis, Ludovit; Thoene-Reineke, Christa; Dahloef, Bjoern; Hallberg, Anders; Unger, Thomas; Sumners, Colin; Steckelings, U. Muscha.

In: Clinical Science, Vol. 128, No. 2, 01.2015, p. 95-109.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Direct angiotensin type 2 receptor (AT(2)R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice

AU - Valero-Esquitino, Veronica

AU - Lucht, Kristin

AU - Namsolleck, Pawel

AU - Monnet-Tschudi, Florianne

AU - Stubbe, Tobias

AU - Lucht, Franziska

AU - Liu, Meng

AU - Ebner, Friederike

AU - Brandt, Christine

AU - Danyel, Leon A.

AU - Villela, Daniel C.

AU - Paulis, Ludovit

AU - Thoene-Reineke, Christa

AU - Dahloef, Bjoern

AU - Hallberg, Anders

AU - Unger, Thomas

AU - Sumners, Colin

AU - Steckelings, U. Muscha

PY - 2015/1

Y1 - 2015/1

KW - angiotensin type 2 receptor (AT(2)R)

KW - experimental autoimmune encephalomyelitis

KW - multiple sclerosis

KW - neuroinflammation

KW - neuroprotection

KW - new therapies

U2 - 10.1042/CS20130601

DO - 10.1042/CS20130601

M3 - Article

C2 - 25052203

VL - 128

SP - 95

EP - 109

JO - Clinical Science

JF - Clinical Science

SN - 0143-5221

IS - 2

ER -