Direct Analysis of Thin-Layer Chromatography Separations of Petroleum Samples by Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Imaging

Donald F. Smith; Amy M. McKenna; Yuri E. Corilo; Ryan P. Rodgers; Alan G. Marshall; Ron M. A. Heeren

doi:10.1021/ef501439w

Direct Analysis of Thin-Layer Chromatography Separations of Petroleum Samples by Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Imaging

Donald F. Smith, Amy M. McKenna, Yuri E. Corilo, Ryan P. Rodgers, Alan G. Marshall, Ron M. A. Heeren^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We present an analytical method for direct analysis of thin-layer chromatography (TLC) separations of petroleum samples by laser desorption ionization (LDI) coupled to Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) imaging. LDI of TLC plates selectively ionizes condensed aromatic hydrocarbons and facilitates two-dimensional imaging of TLC-separated petroleum compounds. Molecular-level characterization available only with ultrahigh-resolution FT-ICR MS provides elemental composition assignment and surpasses conventional TLC readout-based flame ionization detection. Resolution and assignment of migrated molecules targeted by LDI combined with FT-ICR MS provides elemental composition assignment and, therefore, chemical information, i.e., heteroatom class, aromaticity (double bond equivalents), and carbon number. Here, three petroleum samples (a field deposit, a crude oil, and a tar ball) were TLC-separated by their solubility in n-heptane and imaged by LDI FT-ICR MS.

Original language	English
Pages (from-to)	6284-6288
Journal	Energy & Fuels
Volume	28
Issue number	10
DOIs	https://doi.org/10.1021/ef501439w
Publication status	Published - Oct 2014

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10.1021/ef501439w

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@article{0f2ced35a4384d73b5e58263a5af2674,

title = "Direct Analysis of Thin-Layer Chromatography Separations of Petroleum Samples by Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Imaging",

abstract = "We present an analytical method for direct analysis of thin-layer chromatography (TLC) separations of petroleum samples by laser desorption ionization (LDI) coupled to Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) imaging. LDI of TLC plates selectively ionizes condensed aromatic hydrocarbons and facilitates two-dimensional imaging of TLC-separated petroleum compounds. Molecular-level characterization available only with ultrahigh-resolution FT-ICR MS provides elemental composition assignment and surpasses conventional TLC readout-based flame ionization detection. Resolution and assignment of migrated molecules targeted by LDI combined with FT-ICR MS provides elemental composition assignment and, therefore, chemical information, i.e., heteroatom class, aromaticity (double bond equivalents), and carbon number. Here, three petroleum samples (a field deposit, a crude oil, and a tar ball) were TLC-separated by their solubility in n-heptane and imaged by LDI FT-ICR MS.",

author = "Smith, {Donald F.} and McKenna, {Amy M.} and Corilo, {Yuri E.} and Rodgers, {Ryan P.} and Marshall, {Alan G.} and Heeren, {Ron M. A.}",

year = "2014",

month = oct,

doi = "10.1021/ef501439w",

language = "English",

volume = "28",

pages = "6284--6288",

journal = "Energy & Fuels",

issn = "0887-0624",

publisher = "American Chemical Society",

number = "10",

}

Direct Analysis of Thin-Layer Chromatography Separations of Petroleum Samples by Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Imaging. / Smith, Donald F.; McKenna, Amy M.; Corilo, Yuri E. et al.
In: Energy & Fuels, Vol. 28, No. 10, 10.2014, p. 6284-6288.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Direct Analysis of Thin-Layer Chromatography Separations of Petroleum Samples by Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Imaging

AU - Smith, Donald F.

AU - McKenna, Amy M.

AU - Corilo, Yuri E.

AU - Rodgers, Ryan P.

AU - Marshall, Alan G.

AU - Heeren, Ron M. A.

PY - 2014/10

Y1 - 2014/10

N2 - We present an analytical method for direct analysis of thin-layer chromatography (TLC) separations of petroleum samples by laser desorption ionization (LDI) coupled to Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) imaging. LDI of TLC plates selectively ionizes condensed aromatic hydrocarbons and facilitates two-dimensional imaging of TLC-separated petroleum compounds. Molecular-level characterization available only with ultrahigh-resolution FT-ICR MS provides elemental composition assignment and surpasses conventional TLC readout-based flame ionization detection. Resolution and assignment of migrated molecules targeted by LDI combined with FT-ICR MS provides elemental composition assignment and, therefore, chemical information, i.e., heteroatom class, aromaticity (double bond equivalents), and carbon number. Here, three petroleum samples (a field deposit, a crude oil, and a tar ball) were TLC-separated by their solubility in n-heptane and imaged by LDI FT-ICR MS.

AB - We present an analytical method for direct analysis of thin-layer chromatography (TLC) separations of petroleum samples by laser desorption ionization (LDI) coupled to Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) imaging. LDI of TLC plates selectively ionizes condensed aromatic hydrocarbons and facilitates two-dimensional imaging of TLC-separated petroleum compounds. Molecular-level characterization available only with ultrahigh-resolution FT-ICR MS provides elemental composition assignment and surpasses conventional TLC readout-based flame ionization detection. Resolution and assignment of migrated molecules targeted by LDI combined with FT-ICR MS provides elemental composition assignment and, therefore, chemical information, i.e., heteroatom class, aromaticity (double bond equivalents), and carbon number. Here, three petroleum samples (a field deposit, a crude oil, and a tar ball) were TLC-separated by their solubility in n-heptane and imaged by LDI FT-ICR MS.

U2 - 10.1021/ef501439w

DO - 10.1021/ef501439w

M3 - Article

SN - 0887-0624

VL - 28

SP - 6284

EP - 6288

JO - Energy & Fuels

JF - Energy & Fuels

IS - 10

ER -

Direct Analysis of Thin-Layer Chromatography Separations of Petroleum Samples by Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Imaging

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