Diffuse large B-cell lymphoma of the cauda equina

Martijn Broen, Tim Draak, Robert G Riedl, Wim E J Weber

Research output: Contribution to journalArticleAcademicpeer-review


Primary central nervous system (CNS) lymphoma is a rare form of non-Hodgkin's lymphoma. The clinical presentation is variable, depending on its localisation within the nervous system. Only 1% of primary CNS lymphoma emerges in the spinal cord, and the prevalence of primary lymphoma of the cauda equina is unknown, but probably even rarer. Diagnosing primary lymphoma of the cauda equina is difficult, since it can mimic other more common disorders such as a herniated disc, especially in its early stages. Here we present two cases of primary cauda equina lymphoma in which diagnostic work up took a long time, as the final diagnosis was only reached after a nerve root biopsy.

Original languageEnglish
JournalBMJ case Reports
Publication statusPublished - 2014


  • Aged
  • Antineoplastic Combined Chemotherapy Protocols
  • Biopsy
  • Cauda Equina
  • Diagnosis, Differential
  • Fatal Outcome
  • Female
  • Humans
  • Lymphoma, Large B-Cell, Diffuse
  • Paresis
  • Peripheral Nervous System Neoplasms
  • Spinal Nerve Roots

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