Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF

M. Zurek; M.T. Maeder; H. Rickli; S. Muzzarelli; S. Sanders-van Wijk; H. Abbühl; R. Handschin; U. Jeker; M.E. Pfisterer; H.P. Brunner-La Rocca; the TIME-CHF Investigators

doi:10.1016/j.cardfail.2014.12.014

Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF

M. Zurek
, M.T. Maeder^*
, H. Rickli
, S. Muzzarelli
, S. Sanders-van Wijk
, H. Abbühl
, R. Handschin
, U. Jeker
, M.E. Pfisterer
, H.P. Brunner-La Rocca
, the TIME-CHF Investigators

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: There is little information regarding the prognostic role of resting heart rate (HR) in older compared with younger patients with chronic heart failure (HF).

Methods and Results: In patients enrolled in the Trial of Intensified Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) with sinus rhythm, effects of baseline HR (>= 70 vs = 75 years; n = 186) and younger (

Conclusions: In contrast to HF patients aged = 75 years.

Original language	English
Pages (from-to)	347-354
Number of pages	8
Journal	Journal of Cardiac Failure
Volume	21
Issue number	4
DOIs	https://doi.org/10.1016/j.cardfail.2014.12.014
Publication status	Published - Apr 2015

Keywords

Heart rate
chronic heart failure
age
TIME-CHF
prognosis
CORONARY-ARTERY-DISEASE
SYSTOLIC DYSFUNCTION BEAUTIFUL
RANDOMIZED CONTROLLED-TRIAL
STANDARD MEDICAL THERAPY
PLACEBO-CONTROLLED TRIAL
ELDERLY-PATIENTS
RISK-FACTOR
MORTALITY
METOPROLOL
IVABRADINE

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10.1016/j.cardfail.2014.12.014

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Zurek, M., Maeder, M. T., Rickli, H., Muzzarelli, S., Sanders-van Wijk, S., Abbühl, H., Handschin, R., Jeker, U., Pfisterer, M. E., Brunner-La Rocca, H. P., & TIME-CHF Investigators, T. (2015). Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF. Journal of Cardiac Failure, 21(4), 347-354. https://doi.org/10.1016/j.cardfail.2014.12.014

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title = "Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF",

abstract = "Background: There is little information regarding the prognostic role of resting heart rate (HR) in older compared with younger patients with chronic heart failure (HF).Methods and Results: In patients enrolled in the Trial of Intensified Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) with sinus rhythm, effects of baseline HR (>= 70 vs = 75 years; n = 186) and younger (Conclusions: In contrast to HF patients aged = 75 years.",

keywords = "Heart rate, chronic heart failure, age, TIME-CHF, prognosis, CORONARY-ARTERY-DISEASE, SYSTOLIC DYSFUNCTION BEAUTIFUL, RANDOMIZED CONTROLLED-TRIAL, STANDARD MEDICAL THERAPY, PLACEBO-CONTROLLED TRIAL, ELDERLY-PATIENTS, RISK-FACTOR, MORTALITY, METOPROLOL, IVABRADINE",

author = "M. Zurek and M.T. Maeder and H. Rickli and S. Muzzarelli and \{Sanders-van Wijk\}, S. and H. Abb{\"u}hl and R. Handschin and U. Jeker and M.E. Pfisterer and \{Brunner-La Rocca\}, H.P. and \{TIME-CHF Investigators\}, the",

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doi = "10.1016/j.cardfail.2014.12.014",

language = "English",

volume = "21",

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journal = "Journal of Cardiac Failure",

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Zurek, M, Maeder, MT, Rickli, H, Muzzarelli, S, Sanders-van Wijk, S, Abbühl, H, Handschin, R, Jeker, U, Pfisterer, ME, Brunner-La Rocca, HP & TIME-CHF Investigators, T 2015, 'Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF', Journal of Cardiac Failure, vol. 21, no. 4, pp. 347-354. https://doi.org/10.1016/j.cardfail.2014.12.014

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T1 - Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF

AU - Zurek, M.

AU - Maeder, M.T.

AU - Rickli, H.

AU - Muzzarelli, S.

AU - Sanders-van Wijk, S.

AU - Abbühl, H.

AU - Handschin, R.

AU - Jeker, U.

AU - Pfisterer, M.E.

AU - Brunner-La Rocca, H.P.

AU - TIME-CHF Investigators, the

PY - 2015/4

Y1 - 2015/4

N2 - Background: There is little information regarding the prognostic role of resting heart rate (HR) in older compared with younger patients with chronic heart failure (HF).Methods and Results: In patients enrolled in the Trial of Intensified Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) with sinus rhythm, effects of baseline HR (>= 70 vs = 75 years; n = 186) and younger (Conclusions: In contrast to HF patients aged = 75 years.

AB - Background: There is little information regarding the prognostic role of resting heart rate (HR) in older compared with younger patients with chronic heart failure (HF).Methods and Results: In patients enrolled in the Trial of Intensified Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) with sinus rhythm, effects of baseline HR (>= 70 vs = 75 years; n = 186) and younger (Conclusions: In contrast to HF patients aged = 75 years.

KW - Heart rate

KW - chronic heart failure

KW - age

KW - TIME-CHF

KW - prognosis

KW - CORONARY-ARTERY-DISEASE

KW - SYSTOLIC DYSFUNCTION BEAUTIFUL

KW - RANDOMIZED CONTROLLED-TRIAL

KW - STANDARD MEDICAL THERAPY

KW - PLACEBO-CONTROLLED TRIAL

KW - ELDERLY-PATIENTS

KW - RISK-FACTOR

KW - MORTALITY

KW - METOPROLOL

KW - IVABRADINE

U2 - 10.1016/j.cardfail.2014.12.014

DO - 10.1016/j.cardfail.2014.12.014

M3 - Article

C2 - 25576682

SN - 1071-9164

VL - 21

SP - 347

EP - 354

JO - Journal of Cardiac Failure

JF - Journal of Cardiac Failure

IS - 4

ER -

Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF

Abstract

Keywords

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