Differences in heart rate variability between depressed and non-depressed elderly

K.G. van der Kooy; H.P. Hout; H.W.J. Van Marwijk; M. de Haan; C.D.A. Stehouwer; A.T. Beekman

doi:10.1002/gps.1439

Differences in heart rate variability between depressed and non-depressed elderly

K.G. van der Kooy, H.P. Hout^*, H.W.J. Van Marwijk, M. de Haan, C.D.A. Stehouwer, A.T. Beekman

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Objective To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. Method A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched forage and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. Results Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. Conclusion Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.

Original language	English
Pages (from-to)	147-50
Journal	International Journal of Geriatric Psychiatry
Volume	21
DOIs	https://doi.org/10.1002/gps.1439
Publication status	Published - 1 Jan 2006

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title = "Differences in heart rate variability between depressed and non-depressed elderly",

abstract = "Objective To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. Method A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched forage and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. Results Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. Conclusion Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality. ",

author = "{van der Kooy}, K.G. and H.P. Hout and {Van Marwijk}, H.W.J. and {de Haan}, M. and C.D.A. Stehouwer and A.T. Beekman",

year = "2006",

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doi = "10.1002/gps.1439",

language = "English",

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journal = "International Journal of Geriatric Psychiatry",

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TY - JOUR

T1 - Differences in heart rate variability between depressed and non-depressed elderly

AU - van der Kooy, K.G.

AU - Hout, H.P.

AU - Van Marwijk, H.W.J.

AU - de Haan, M.

AU - Stehouwer, C.D.A.

AU - Beekman, A.T.

PY - 2006/1/1

Y1 - 2006/1/1

N2 - Objective To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. Method A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched forage and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. Results Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. Conclusion Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.

AB - Objective To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. Method A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched forage and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. Results Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. Conclusion Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.

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DO - 10.1002/gps.1439

M3 - Article

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SN - 0885-6230

VL - 21

SP - 147

EP - 150

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

ER -

Differences in heart rate variability between depressed and non-depressed elderly

Abstract

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