Dietary polyphenols: modulators of energy and substrate metabolism in obese humans

J. Most

Research output: ThesisDoctoral ThesisInternal

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Nearly 50% of the world's population is overweight, which has triggered an increase in weight-related diseases like diabetes. Since dieting and a more active lifestyle are not always successful, we investigated whether taking polyphenols, which are natural plant ingredients found in green tea and red wine, would improve the health and metabolic profile of overweight men and women.

After twelve weeks of polyphenol supplementation, the supplements appeared to stimulate the fat-burning capacity of the muscles. This improvement may contribute to preventing obesity and weight-related diseases like diabetes in the long term. Further research is required to confirm this.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • Blaak, Ellen, Supervisor
  • Goossens, Gijs, Co-Supervisor
Award date15 Jan 2016
Place of PublicationMaastricht
Publication statusPublished - 1 Jan 2016


  • obesity
  • dietary supplements
  • polyphenols
  • fat oxidation

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