Dietary Intake after Weight Loss and the Risk of Weight Regain: Macronutrient Composition and Inflammatory Properties of the Diet

Harry Freitag Luglio Muhammad*, Roel G. Vink, Nadia J. T. Roumans, Laura A. J. Arkenbosch, Edwin C. Mariman, Marleen A. van Baak

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Web of Science)

Abstract

Weight regain after successful weight loss is a big problem in obesity management. This study aimed to investigate whether weight regain after a weight loss period is correlated with the macronutrient composition and/or the inflammatory index of the diet during that period. Sixty one overweight and obese adults participated in this experimental study. Subjects lost approximately 10% of their initial weight by means of very low-calorie diet for five weeks, or a low calorie diet for 12 weeks. After that, subjects in both groups followed a strict weight maintenance diet based on individual needs for four weeks, which was followed by a nine-month weight maintenance period without dietary counseling. Anthropometrics and dietary intake data were recorded before weight loss (baseline) and during the weight maintenance period. On average, participants regained approximately half of their lost weight. We found no evidence that macronutrient composition during the weight maintenance period was associated with weight regain. The dietary inflammatory index (r = 0.304, p = 0.032) was positively correlated with weight regain and remained significant after correction for physical activity (r = 0.287, p = 0.045). Our data suggest that the inflammatory properties of diet play a role in weight regain after weight loss in overweight and obese adults.

Original languageEnglish
Article number1205
Number of pages11
JournalNutrients
Volume9
Issue number11
DOIs
Publication statusPublished - Nov 2017

Keywords

  • obesity
  • weight regain
  • macronutrient composition
  • inflammation
  • LOW-PROTEIN CONTENT
  • LOSS MAINTENANCE
  • OVERWEIGHT SUBJECTS
  • INSULIN-RESISTANCE
  • ADIPOSE-TISSUE
  • GLYCEMIC INDEX
  • OBESITY
  • ADULTS
  • TRIAL
  • MARKERS

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