Dietary arginine and linear growth: the Copenhagen School Child Intervention Study

Anneke J. A. H. van Vught; Pieter C. Dagnelie; Ilja C. W. Arts; Karsten Froberg; Lars B. Andersen; Bianca El-Naaman; Anna Bugge; Birgit M. Nielsen; Berit L. Heitman

doi:10.1017/S0007114512002942

Dietary arginine and linear growth: the Copenhagen School Child Intervention Study

Anneke J. A. H. van Vught^*, Pieter C. Dagnelie, Ilja C. W. Arts, Karsten Froberg, Lars B. Andersen, Bianca El-Naaman, Anna Bugge, Birgit M. Nielsen, Berit L. Heitman

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Web of Science)

Abstract

The amino acid arginine is a well-known growth hormone (GH) stimulator and GH is an important modulator of linear growth. The aim of the present study was to investigate the effect of dietary arginine on growth velocity in children between 7 and 13 years of age. Data from the Copenhagen School Child Intervention Study during 2001-2 (baseline), and at 3-year and 7-year follow-up, were used. Arginine intake was estimated via a 7 d precoded food diary at baseline and 3-year follow-up. Data were analysed in a multilevel structure in which children were embedded within schools. Random intercept and slopes were defined to estimate the association between arginine intake and growth velocity, including the following covariates: sex; age; baseline height; energy intake; puberty stage at 7-year follow-up and intervention/control group. The association between arginine intake and growth velocity was significant for the third and fourth quintile of arginine intake (2.5-2.8 and 2.8-3.2 g/d, respectively) compared with the first quintile (

Original language	English
Pages (from-to)	1031-1039
Journal	British Journal of Nutrition
Volume	109
Issue number	6
DOIs	https://doi.org/10.1017/S0007114512002942
Publication status	Published - 28 Mar 2013

Keywords

Arginine
Linear growth
Growth hormone

Access to Document

10.1017/S0007114512002942

Cite this

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title = "Dietary arginine and linear growth: the Copenhagen School Child Intervention Study",

abstract = "The amino acid arginine is a well-known growth hormone (GH) stimulator and GH is an important modulator of linear growth. The aim of the present study was to investigate the effect of dietary arginine on growth velocity in children between 7 and 13 years of age. Data from the Copenhagen School Child Intervention Study during 2001-2 (baseline), and at 3-year and 7-year follow-up, were used. Arginine intake was estimated via a 7 d precoded food diary at baseline and 3-year follow-up. Data were analysed in a multilevel structure in which children were embedded within schools. Random intercept and slopes were defined to estimate the association between arginine intake and growth velocity, including the following covariates: sex; age; baseline height; energy intake; puberty stage at 7-year follow-up and intervention/control group. The association between arginine intake and growth velocity was significant for the third and fourth quintile of arginine intake (2.5-2.8 and 2.8-3.2 g/d, respectively) compared with the first quintile (",

keywords = "Arginine, Linear growth, Growth hormone",

author = "{van Vught}, {Anneke J. A. H.} and Dagnelie, {Pieter C.} and Arts, {Ilja C. W.} and Karsten Froberg and Andersen, {Lars B.} and Bianca El-Naaman and Anna Bugge and Nielsen, {Birgit M.} and Heitman, {Berit L.}",

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T1 - Dietary arginine and linear growth: the Copenhagen School Child Intervention Study

AU - van Vught, Anneke J. A. H.

AU - Dagnelie, Pieter C.

AU - Arts, Ilja C. W.

AU - Froberg, Karsten

AU - Andersen, Lars B.

AU - El-Naaman, Bianca

AU - Bugge, Anna

AU - Nielsen, Birgit M.

AU - Heitman, Berit L.

PY - 2013/3/28

Y1 - 2013/3/28

N2 - The amino acid arginine is a well-known growth hormone (GH) stimulator and GH is an important modulator of linear growth. The aim of the present study was to investigate the effect of dietary arginine on growth velocity in children between 7 and 13 years of age. Data from the Copenhagen School Child Intervention Study during 2001-2 (baseline), and at 3-year and 7-year follow-up, were used. Arginine intake was estimated via a 7 d precoded food diary at baseline and 3-year follow-up. Data were analysed in a multilevel structure in which children were embedded within schools. Random intercept and slopes were defined to estimate the association between arginine intake and growth velocity, including the following covariates: sex; age; baseline height; energy intake; puberty stage at 7-year follow-up and intervention/control group. The association between arginine intake and growth velocity was significant for the third and fourth quintile of arginine intake (2.5-2.8 and 2.8-3.2 g/d, respectively) compared with the first quintile (

AB - The amino acid arginine is a well-known growth hormone (GH) stimulator and GH is an important modulator of linear growth. The aim of the present study was to investigate the effect of dietary arginine on growth velocity in children between 7 and 13 years of age. Data from the Copenhagen School Child Intervention Study during 2001-2 (baseline), and at 3-year and 7-year follow-up, were used. Arginine intake was estimated via a 7 d precoded food diary at baseline and 3-year follow-up. Data were analysed in a multilevel structure in which children were embedded within schools. Random intercept and slopes were defined to estimate the association between arginine intake and growth velocity, including the following covariates: sex; age; baseline height; energy intake; puberty stage at 7-year follow-up and intervention/control group. The association between arginine intake and growth velocity was significant for the third and fourth quintile of arginine intake (2.5-2.8 and 2.8-3.2 g/d, respectively) compared with the first quintile (

KW - Arginine

KW - Linear growth

KW - Growth hormone

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