Diet induced thermogenesis measured over 24h in a respiration chamber: effect of diet composition.

K.R. Westerterp*, S.A. Wilson, V. Rolland

*Corresponding author for this work

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Department of Human Biology, Maastricht University, The Netherlands.

OBJECTIVE: To study the effect of diet composition on diet-induced thermogenesis (DIT) over 24h in a respiration chamber. SUBJECTS: Eight healthy female volunteers (age 27 +/- 3 y; body mass index, BMI 23 +/- 3 kg/m2). DIETS: A high protein and carbohydrate (HP/C) (60:10:30; percentage energy (E%)carbohydrate, fat and protein, respectively) and high fat (HF) (30:60:10 respectively) diet, both isoenergetic, isovolumetric, composed of normal food items and matched for organoleptic properties (taste, smell, appearance). DESIGN: Subjects spent two 36h periods each in a respiration chamber consuming both test diets in random order. Components of 24h energy expenditure (24h EE): sleeping metabolic rate, DIT and activity induced energy expenditure were measured. RESULTS: DIT was higher in all subjects while on the HP/C diet (1295 kJ/d vs 931 kJ/d; 14.6% vs 10.5% of energy intake; P < 0.02). There was no significant difference in other components or total 24h EE, although there was a trend towards higher EE on the HP/C diet. CONCLUSION: A high protein and carbohydrate diet induces a greater thermic response in healthy individuals when compared to a high fat diet.

Publication Types:
Clinical Trial
Randomized Controlled Trial
Original languageEnglish
Pages (from-to)287-292
Number of pages6
JournalInternational Journal of Obesity
Issue number3
Publication statusPublished - 1 Jan 1999

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