Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

Claire Bridel; Wessel N. van Wieringen; Henrik Zetterberg; Betty M. Tijms; Charlotte E. Teunissen; Jose C. Alvarez-Cermeno; Ulf Andreasson; Markus Axelsson; David C. Backstrom; Ales Bartos; Maria Bjerke; Kaj Blennow; Adam Boxer; Lou Brundin; Joachim Burman; Tove Christensen; Lenka Fialova; Lars Forsgren; Jette L. Frederiksen; Magnus Gisslen; Elizabeth Gray; Martin Gunnarsson; Sara Hall; Oskar Hansson; Megan K. Herbert; Joel Jakobsson; Jan Jessen-Krut; Shorena Janelidze; Gudmundur Johannsson; Michael Jonsson; Ludwig Kappos; Mohsen Khademi; Michael Khalil; Jens Kuhle; Mikael Landen; Ville Leinonen; Giancarlo Logroscino; Ching-Hua Lu; Jan Lycke; Nadia K. Magdalinou; Andrea Malaspina; Niklas Mattsson; Lieke H. Meeter; Sanjay R. Mehta; Signe Modvig; Tomas Olsson; Ross W. Paterson; Josue Perez-Santiago; Fredrik Piehl; Pieter Jelle Visser; NFL Group

doi:10.1001/jamaneurol.2019.1534

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

Claire Bridel^*, Wessel N. van Wieringen, Henrik Zetterberg, Betty M. Tijms, Charlotte E. Teunissen, Jose C. Alvarez-Cermeno, Ulf Andreasson, Markus Axelsson, David C. Backstrom, Ales Bartos, Maria Bjerke, Kaj Blennow, Adam Boxer, Lou Brundin, Joachim Burman, Tove Christensen, Lenka Fialova, Lars Forsgren, Jette L. Frederiksen, Magnus GisslenElizabeth Gray, Martin Gunnarsson, Sara Hall, Oskar Hansson, Megan K. Herbert, Joel Jakobsson, Jan Jessen-Krut, Shorena Janelidze, Gudmundur Johannsson, Michael Jonsson, Ludwig Kappos, Mohsen Khademi, Michael Khalil, Jens Kuhle, Mikael Landen, Ville Leinonen, Giancarlo Logroscino, Ching-Hua Lu, Jan Lycke, Nadia K. Magdalinou, Andrea Malaspina, Niklas Mattsson, Lieke H. Meeter, Sanjay R. Mehta, Signe Modvig, Tomas Olsson, Ross W. Paterson, Josue Perez-Santiago, Fredrik Piehl, Pieter Jelle Visser, NFL Group

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

160 Citations (Web of Science)

Original language	English
Pages (from-to)	1035-1048
Number of pages	14
Journal	JAMA Neurology
Volume	76
Issue number	9
DOIs	https://doi.org/10.1001/jamaneurol.2019.1534
Publication status	Published - Sep 2019

Keywords

AMYOTROPHIC-LATERAL-SCLEROSIS
FIBRILLARY ACIDIC PROTEIN
CSF NEUROFILAMENT
MULTIPLE-SCLEROSIS
ALZHEIMERS-DISEASE
AXONAL DAMAGE
NEURODEGENERATIVE DISEASES
PARKINSONS-DISEASE
CLINICAL-DIAGNOSIS
NATIONAL INSTITUTE

Access to Document

10.1001/jamaneurol.2019.1534

Cite this

Bridel, C., van Wieringen, W. N., Zetterberg, H., Tijms, B. M., Teunissen, C. E., Alvarez-Cermeno, J. C., Andreasson, U., Axelsson, M., Backstrom, D. C., Bartos, A., Bjerke, M., Blennow, K., Boxer, A., Brundin, L., Burman, J., Christensen, T., Fialova, L., Forsgren, L., Frederiksen, J. L., ... NFL Group (2019). Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis. JAMA Neurology, 76(9), 1035-1048. https://doi.org/10.1001/jamaneurol.2019.1534

Bridel, Claire ; van Wieringen, Wessel N. ; Zetterberg, Henrik ; Tijms, Betty M. ; Teunissen, Charlotte E. ; Alvarez-Cermeno, Jose C. ; Andreasson, Ulf ; Axelsson, Markus ; Backstrom, David C. ; Bartos, Ales ; Bjerke, Maria ; Blennow, Kaj ; Boxer, Adam ; Brundin, Lou ; Burman, Joachim ; Christensen, Tove ; Fialova, Lenka ; Forsgren, Lars ; Frederiksen, Jette L. ; Gisslen, Magnus ; Gray, Elizabeth ; Gunnarsson, Martin ; Hall, Sara ; Hansson, Oskar ; Herbert, Megan K. ; Jakobsson, Joel ; Jessen-Krut, Jan ; Janelidze, Shorena ; Johannsson, Gudmundur ; Jonsson, Michael ; Kappos, Ludwig ; Khademi, Mohsen ; Khalil, Michael ; Kuhle, Jens ; Landen, Mikael ; Leinonen, Ville ; Logroscino, Giancarlo ; Lu, Ching-Hua ; Lycke, Jan ; Magdalinou, Nadia K. ; Malaspina, Andrea ; Mattsson, Niklas ; Meeter, Lieke H. ; Mehta, Sanjay R. ; Modvig, Signe ; Olsson, Tomas ; Paterson, Ross W. ; Perez-Santiago, Josue ; Piehl, Fredrik ; Visser, Pieter Jelle ; NFL Group. / Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology : A Systematic Review and Meta-analysis. In: JAMA Neurology. 2019 ; Vol. 76, No. 9. pp. 1035-1048.

@article{6fbcf3cfc7e242b8aef418641efa614f,

title = "Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis",

keywords = "AMYOTROPHIC-LATERAL-SCLEROSIS, FIBRILLARY ACIDIC PROTEIN, CSF NEUROFILAMENT, MULTIPLE-SCLEROSIS, ALZHEIMERS-DISEASE, AXONAL DAMAGE, NEURODEGENERATIVE DISEASES, PARKINSONS-DISEASE, CLINICAL-DIAGNOSIS, NATIONAL INSTITUTE",

author = "Claire Bridel and {van Wieringen}, {Wessel N.} and Henrik Zetterberg and Tijms, {Betty M.} and Teunissen, {Charlotte E.} and Alvarez-Cermeno, {Jose C.} and Ulf Andreasson and Markus Axelsson and Backstrom, {David C.} and Ales Bartos and Maria Bjerke and Kaj Blennow and Adam Boxer and Lou Brundin and Joachim Burman and Tove Christensen and Lenka Fialova and Lars Forsgren and Frederiksen, {Jette L.} and Magnus Gisslen and Elizabeth Gray and Martin Gunnarsson and Sara Hall and Oskar Hansson and Herbert, {Megan K.} and Joel Jakobsson and Jan Jessen-Krut and Shorena Janelidze and Gudmundur Johannsson and Michael Jonsson and Ludwig Kappos and Mohsen Khademi and Michael Khalil and Jens Kuhle and Mikael Landen and Ville Leinonen and Giancarlo Logroscino and Ching-Hua Lu and Jan Lycke and Magdalinou, {Nadia K.} and Andrea Malaspina and Niklas Mattsson and Meeter, {Lieke H.} and Mehta, {Sanjay R.} and Signe Modvig and Tomas Olsson and Paterson, {Ross W.} and Josue Perez-Santiago and Fredrik Piehl and Visser, {Pieter Jelle} and {NFL Group}",

year = "2019",

month = sep,

doi = "10.1001/jamaneurol.2019.1534",

language = "English",

volume = "76",

pages = "1035--1048",

journal = "JAMA Neurology",

issn = "2168-6149",

publisher = "American Medical Association",

number = "9",

}

Bridel, C, van Wieringen, WN, Zetterberg, H, Tijms, BM, Teunissen, CE, Alvarez-Cermeno, JC, Andreasson, U, Axelsson, M, Backstrom, DC, Bartos, A, Bjerke, M, Blennow, K, Boxer, A, Brundin, L, Burman, J, Christensen, T, Fialova, L, Forsgren, L, Frederiksen, JL, Gisslen, M, Gray, E, Gunnarsson, M, Hall, S, Hansson, O, Herbert, MK, Jakobsson, J, Jessen-Krut, J, Janelidze, S, Johannsson, G, Jonsson, M, Kappos, L, Khademi, M, Khalil, M, Kuhle, J, Landen, M, Leinonen, V, Logroscino, G, Lu, C-H, Lycke, J, Magdalinou, NK, Malaspina, A, Mattsson, N, Meeter, LH, Mehta, SR, Modvig, S, Olsson, T, Paterson, RW, Perez-Santiago, J, Piehl, F, Visser, PJ & NFL Group 2019, 'Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis', JAMA Neurology, vol. 76, no. 9, pp. 1035-1048. https://doi.org/10.1001/jamaneurol.2019.1534

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology : A Systematic Review and Meta-analysis. / Bridel, Claire; van Wieringen, Wessel N.; Zetterberg, Henrik; Tijms, Betty M.; Teunissen, Charlotte E.; Alvarez-Cermeno, Jose C.; Andreasson, Ulf; Axelsson, Markus; Backstrom, David C.; Bartos, Ales; Bjerke, Maria; Blennow, Kaj; Boxer, Adam; Brundin, Lou; Burman, Joachim; Christensen, Tove; Fialova, Lenka; Forsgren, Lars; Frederiksen, Jette L.; Gisslen, Magnus; Gray, Elizabeth; Gunnarsson, Martin; Hall, Sara; Hansson, Oskar; Herbert, Megan K.; Jakobsson, Joel; Jessen-Krut, Jan; Janelidze, Shorena; Johannsson, Gudmundur; Jonsson, Michael; Kappos, Ludwig; Khademi, Mohsen; Khalil, Michael; Kuhle, Jens; Landen, Mikael; Leinonen, Ville; Logroscino, Giancarlo; Lu, Ching-Hua; Lycke, Jan; Magdalinou, Nadia K.; Malaspina, Andrea; Mattsson, Niklas; Meeter, Lieke H.; Mehta, Sanjay R.; Modvig, Signe; Olsson, Tomas; Paterson, Ross W.; Perez-Santiago, Josue; Piehl, Fredrik; Visser, Pieter Jelle; NFL Group.

In: JAMA Neurology, Vol. 76, No. 9, 09.2019, p. 1035-1048.

Research output: Contribution to journal › Review article › Academic › peer-review

TY - JOUR

T1 - Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology

T2 - A Systematic Review and Meta-analysis

AU - Bridel, Claire

AU - van Wieringen, Wessel N.

AU - Zetterberg, Henrik

AU - Tijms, Betty M.

AU - Teunissen, Charlotte E.

AU - Alvarez-Cermeno, Jose C.

AU - Andreasson, Ulf

AU - Axelsson, Markus

AU - Backstrom, David C.

AU - Bartos, Ales

AU - Bjerke, Maria

AU - Blennow, Kaj

AU - Boxer, Adam

AU - Brundin, Lou

AU - Burman, Joachim

AU - Christensen, Tove

AU - Fialova, Lenka

AU - Forsgren, Lars

AU - Frederiksen, Jette L.

AU - Gisslen, Magnus

AU - Gray, Elizabeth

AU - Gunnarsson, Martin

AU - Hall, Sara

AU - Hansson, Oskar

AU - Herbert, Megan K.

AU - Jakobsson, Joel

AU - Jessen-Krut, Jan

AU - Janelidze, Shorena

AU - Johannsson, Gudmundur

AU - Jonsson, Michael

AU - Kappos, Ludwig

AU - Khademi, Mohsen

AU - Khalil, Michael

AU - Kuhle, Jens

AU - Landen, Mikael

AU - Leinonen, Ville

AU - Logroscino, Giancarlo

AU - Lu, Ching-Hua

AU - Lycke, Jan

AU - Magdalinou, Nadia K.

AU - Malaspina, Andrea

AU - Mattsson, Niklas

AU - Meeter, Lieke H.

AU - Mehta, Sanjay R.

AU - Modvig, Signe

AU - Olsson, Tomas

AU - Paterson, Ross W.

AU - Perez-Santiago, Josue

AU - Piehl, Fredrik

AU - Visser, Pieter Jelle

AU - NFL Group

PY - 2019/9

Y1 - 2019/9

KW - AMYOTROPHIC-LATERAL-SCLEROSIS

KW - FIBRILLARY ACIDIC PROTEIN

KW - CSF NEUROFILAMENT

KW - MULTIPLE-SCLEROSIS

KW - ALZHEIMERS-DISEASE

KW - AXONAL DAMAGE

KW - NEURODEGENERATIVE DISEASES

KW - PARKINSONS-DISEASE

KW - CLINICAL-DIAGNOSIS

KW - NATIONAL INSTITUTE

U2 - 10.1001/jamaneurol.2019.1534

DO - 10.1001/jamaneurol.2019.1534

M3 - Review article

VL - 76

SP - 1035

EP - 1048

JO - JAMA Neurology

JF - JAMA Neurology

SN - 2168-6149

IS - 9

ER -