Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations

Desiree Abdurrachim; Miranda Nabben; Verena Hoerr; Michael T. Kuhlmann; Philipp Bovenkamp; Jolita Ciapaite; Ilvy M. E. Geraets; Will Coumans; Joost J. F. P. Luiken; Jan F. C. Glatz; Michael Schaefers; Klaas Nicolay; Cornelius Faber; Sven Hermann; Jeanine J. Prompers

doi:10.1093/cvr/cvx100

Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations

Desiree Abdurrachim, Miranda Nabben, Verena Hoerr, Michael T. Kuhlmann, Philipp Bovenkamp, Jolita Ciapaite, Ilvy M. E. Geraets, Will Coumans, Joost J. F. P. Luiken, Jan F. C. Glatz, Michael Schaefers, Klaas Nicolay, Cornelius Faber, Sven Hermann, Jeanine J. Prompers^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1148-1160
Number of pages	13
Journal	Cardiovascular Research
Volume	113
Issue number	10
DOIs	https://doi.org/10.1093/cvr/cvx100
Publication status	Published - 1 Aug 2017

Keywords

Heart failure
Pressure overload
Diabetes
Substrate metabolism
In vivo imaging techniques
FATTY-ACID OXIDATION
ENERGY PHOSPHATE METABOLITES
ACTIVATED-RECEPTOR-ALPHA
PROTEIN-KINASE D1
DILATED CARDIOMYOPATHY
GLUCOSE-METABOLISM
DIASTOLIC DYSFUNCTION
INSULIN-RESISTANCE
HYPERTROPHY
PREVENTS

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10.1093/cvr/cvx100

Cite this

Abdurrachim, D., Nabben, M., Hoerr, V., Kuhlmann, M. T., Bovenkamp, P., Ciapaite, J., Geraets, I. M. E., Coumans, W., Luiken, J. J. F. P., Glatz, J. F. C., Schaefers, M., Nicolay, K., Faber, C., Hermann, S., & Prompers, J. J. (2017). Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovascular Research, 113(10), 1148-1160. https://doi.org/10.1093/cvr/cvx100

Abdurrachim, Desiree ; Nabben, Miranda ; Hoerr, Verena ; Kuhlmann, Michael T. ; Bovenkamp, Philipp ; Ciapaite, Jolita ; Geraets, Ilvy M. E. ; Coumans, Will ; Luiken, Joost J. F. P. ; Glatz, Jan F. C. ; Schaefers, Michael ; Nicolay, Klaas ; Faber, Cornelius ; Hermann, Sven ; Prompers, Jeanine J. / Diabetic db/db mice do not develop heart failure upon pressure overload : a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. In: Cardiovascular Research. 2017 ; Vol. 113, No. 10. pp. 1148-1160.

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title = "Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations",

keywords = "Heart failure, Pressure overload, Diabetes, Substrate metabolism, In vivo imaging techniques, FATTY-ACID OXIDATION, ENERGY PHOSPHATE METABOLITES, ACTIVATED-RECEPTOR-ALPHA, PROTEIN-KINASE D1, DILATED CARDIOMYOPATHY, GLUCOSE-METABOLISM, DIASTOLIC DYSFUNCTION, INSULIN-RESISTANCE, HYPERTROPHY, PREVENTS",

author = "Desiree Abdurrachim and Miranda Nabben and Verena Hoerr and Kuhlmann, {Michael T.} and Philipp Bovenkamp and Jolita Ciapaite and Geraets, {Ilvy M. E.} and Will Coumans and Luiken, {Joost J. F. P.} and Glatz, {Jan F. C.} and Michael Schaefers and Klaas Nicolay and Cornelius Faber and Sven Hermann and Prompers, {Jeanine J.}",

year = "2017",

month = aug,

day = "1",

doi = "10.1093/cvr/cvx100",

language = "English",

volume = "113",

pages = "1148--1160",

journal = "Cardiovascular Research",

issn = "0008-6363",

publisher = "Oxford University Press",

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Abdurrachim, D, Nabben, M, Hoerr, V, Kuhlmann, MT, Bovenkamp, P, Ciapaite, J, Geraets, IME, Coumans, W, Luiken, JJFP , Glatz, JFC, Schaefers, M, Nicolay, K, Faber, C, Hermann, S & Prompers, JJ 2017, 'Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations', Cardiovascular Research, vol. 113, no. 10, pp. 1148-1160. https://doi.org/10.1093/cvr/cvx100

Diabetic db/db mice do not develop heart failure upon pressure overload : a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. / Abdurrachim, Desiree; Nabben, Miranda; Hoerr, Verena; Kuhlmann, Michael T.; Bovenkamp, Philipp; Ciapaite, Jolita; Geraets, Ilvy M. E.; Coumans, Will; Luiken, Joost J. F. P.; Glatz, Jan F. C.; Schaefers, Michael; Nicolay, Klaas; Faber, Cornelius; Hermann, Sven; Prompers, Jeanine J.

In: Cardiovascular Research, Vol. 113, No. 10, 01.08.2017, p. 1148-1160.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Diabetic db/db mice do not develop heart failure upon pressure overload

T2 - a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations

AU - Abdurrachim, Desiree

AU - Nabben, Miranda

AU - Hoerr, Verena

AU - Kuhlmann, Michael T.

AU - Bovenkamp, Philipp

AU - Ciapaite, Jolita

AU - Geraets, Ilvy M. E.

AU - Coumans, Will

AU - Luiken, Joost J. F. P.

AU - Glatz, Jan F. C.

AU - Schaefers, Michael

AU - Nicolay, Klaas

AU - Faber, Cornelius

AU - Hermann, Sven

AU - Prompers, Jeanine J.

PY - 2017/8/1

Y1 - 2017/8/1

KW - Heart failure

KW - Pressure overload

KW - Diabetes

KW - Substrate metabolism

KW - In vivo imaging techniques

KW - FATTY-ACID OXIDATION

KW - ENERGY PHOSPHATE METABOLITES

KW - ACTIVATED-RECEPTOR-ALPHA

KW - PROTEIN-KINASE D1

KW - DILATED CARDIOMYOPATHY

KW - GLUCOSE-METABOLISM

KW - DIASTOLIC DYSFUNCTION

KW - INSULIN-RESISTANCE

KW - HYPERTROPHY

KW - PREVENTS

U2 - 10.1093/cvr/cvx100

DO - 10.1093/cvr/cvx100

M3 - Article

VL - 113

SP - 1148

EP - 1160

JO - Cardiovascular Research

JF - Cardiovascular Research

SN - 0008-6363

IS - 10

ER -