TY - JOUR
T1 - Dexmedetomidine to Treat 3, 4-Methylenedioxymethamphetamine-Induced Agitation in a 13-Month-Old Infant
T2 - A Case Report and Literature Review
AU - Sanders, Patricia J. L. T.
AU - Hanot, Jan
PY - 2019/9
Y1 - 2019/9
N2 - We report a 13-month-old infant who accidentally ingested a tablet of 3, 4-methylenedioxymethamphetamine (MDMA) and was brought to the emergency department with tachycardia, seizures, mydriasis, and altered mental status. The patient received multiple doses of benzodiazepines to treat the seizures and developed respiratory insufficiency needing intubation. After extubation, the patient developed hyperactivity, myoclonic, and choreoathetoid movements which were unresponsive to benzodiazepines. Dexmedetomidine was started with good response. The patient made a full clinical recovery. This is the first case that illustrates the possibility to treat MDMA-induced agitation with dexmedetomidine in a 13-month-old infant.
AB - We report a 13-month-old infant who accidentally ingested a tablet of 3, 4-methylenedioxymethamphetamine (MDMA) and was brought to the emergency department with tachycardia, seizures, mydriasis, and altered mental status. The patient received multiple doses of benzodiazepines to treat the seizures and developed respiratory insufficiency needing intubation. After extubation, the patient developed hyperactivity, myoclonic, and choreoathetoid movements which were unresponsive to benzodiazepines. Dexmedetomidine was started with good response. The patient made a full clinical recovery. This is the first case that illustrates the possibility to treat MDMA-induced agitation with dexmedetomidine in a 13-month-old infant.
KW - MDMA
KW - dexmedetomidine
KW - infant
KW - 3,4-METHYLENEDIOXYMETHAMPHETAMINE
KW - AMPHETAMINE
U2 - 10.1055/s-0039-1677815
DO - 10.1055/s-0039-1677815
M3 - (Systematic) Review article
C2 - 31404223
SN - 2146-4618
VL - 8
SP - 175
EP - 177
JO - Journal of Pediatric Intensive Care
JF - Journal of Pediatric Intensive Care
IS - 3
ER -