Development of functional biomaterials by a design-driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing-driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it.
Danoux, C., Sun, L., Kocer, G., Birgani, Z. T., Barata, D., Barralet, J., van Blitterswijk, C., Truckenmuller, R., & Habibovic, P. (2016). Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties. Advanced Materials, 28(9), 1803-1808. https://doi.org/10.1002/adma.201504589