Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties

Charlene Danoux; Lanying Sun; Gulistan Kocer; Zeinab Tahmasebi Birgani; David Barata; Jake Barralet; Clemens van Blitterswijk; Roman Truckenmuller; Pamela Habibovic

doi:10.1002/adma.201504589

Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties

Charlene Danoux, Lanying Sun, Gulistan Kocer, Zeinab Tahmasebi Birgani, David Barata, Jake Barralet, Clemens van Blitterswijk, Roman Truckenmuller, Pamela Habibovic^*

^*Corresponding author for this work

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Abstract

Development of functional biomaterials by a design-driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing-driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it.

Original language	English
Pages (from-to)	1803-1808
Journal	Advanced Materials
Volume	28
Issue number	9
DOIs	https://doi.org/10.1002/adma.201504589
Publication status	Published - 2 Mar 2016

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title = "Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties",

abstract = "Development of functional biomaterials by a design-driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing-driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it.",

author = "Charlene Danoux and Lanying Sun and Gulistan Kocer and Birgani, {Zeinab Tahmasebi} and David Barata and Jake Barralet and {van Blitterswijk}, Clemens and Roman Truckenmuller and Pamela Habibovic",

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AU - Danoux, Charlene

AU - Sun, Lanying

AU - Kocer, Gulistan

AU - Birgani, Zeinab Tahmasebi

AU - Barata, David

AU - Barralet, Jake

AU - van Blitterswijk, Clemens

AU - Truckenmuller, Roman

AU - Habibovic, Pamela

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AB - Development of functional biomaterials by a design-driven approach is described, whereby individual properties are first decoupled to investigate their sole effects on a biological process. Following this investigation, they are recombined in such a way that the overall performance and applicability of the biomaterial is improved. This is in contrast to classical, processing-driven biomaterials development where the properties of a material are mainly determined by the possibilities of the technique used to produce it.

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DO - 10.1002/adma.201504589

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JO - Advanced Materials

JF - Advanced Materials

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Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties

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