Development of a Prognostic Nomogram for Patients with Peritoneally Metastasized Colorectal Cancer Treated with Cytoreductive Surgery and HIPEC

Geert A. Simkens; Thijs R. van Oudheusden; Daan Nieboer; Ewout W. Steyerberg; Harm J. Rutten; Misha D. Luyer; Simon W. Nienhuijs; Ignace H. de Hingh

doi:10.1245/s10434-016-5211-6

Development of a Prognostic Nomogram for Patients with Peritoneally Metastasized Colorectal Cancer Treated with Cytoreductive Surgery and HIPEC

Geert A. Simkens
, Thijs R. van Oudheusden
, Daan Nieboer
, Ewout W. Steyerberg
, Harm J. Rutten
, Misha D. Luyer
, Simon W. Nienhuijs
, Ignace H. de Hingh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

With the introduction of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), long-term survival can be achieved in selected patients with colorectal peritoneal metastases (PM). Patient selection and outcome may be improved significantly with a tool that adequately predicts survival in these patients. This study was designed to validate the peritoneal surface disease severity score (PSDSS) in patients with colorectal PM treated with CRS?+?HIPEC. If performance of the PSDSS was suboptimal (c?

Original language	English
Pages (from-to)	4214-4221
Number of pages	8
Journal	Annals of Surgical Oncology
Volume	23
Issue number	13
DOIs	https://doi.org/10.1245/s10434-016-5211-6
Publication status	Published - Dec 2016

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10.1245/s10434-016-5211-6

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Simkens, G. A., van Oudheusden, T. R., Nieboer, D., Steyerberg, E. W., Rutten, H. J., Luyer, M. D., Nienhuijs, S. W., & de Hingh, I. H. (2016). Development of a Prognostic Nomogram for Patients with Peritoneally Metastasized Colorectal Cancer Treated with Cytoreductive Surgery and HIPEC. Annals of Surgical Oncology, 23(13), 4214-4221. https://doi.org/10.1245/s10434-016-5211-6

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title = "Development of a Prognostic Nomogram for Patients with Peritoneally Metastasized Colorectal Cancer Treated with Cytoreductive Surgery and HIPEC",

abstract = "With the introduction of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), long-term survival can be achieved in selected patients with colorectal peritoneal metastases (PM). Patient selection and outcome may be improved significantly with a tool that adequately predicts survival in these patients. This study was designed to validate the peritoneal surface disease severity score (PSDSS) in patients with colorectal PM treated with CRS?+?HIPEC. If performance of the PSDSS was suboptimal (c?",

author = "Simkens, \{Geert A.\} and \{van Oudheusden\}, \{Thijs R.\} and Daan Nieboer and Steyerberg, \{Ewout W.\} and Rutten, \{Harm J.\} and Luyer, \{Misha D.\} and Nienhuijs, \{Simon W.\} and \{de Hingh\}, \{Ignace H.\}",

year = "2016",

month = dec,

doi = "10.1245/s10434-016-5211-6",

language = "English",

volume = "23",

pages = "4214--4221",

journal = "Annals of Surgical Oncology",

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AU - Simkens, Geert A.

AU - van Oudheusden, Thijs R.

AU - Nieboer, Daan

AU - Steyerberg, Ewout W.

AU - Rutten, Harm J.

AU - Luyer, Misha D.

AU - Nienhuijs, Simon W.

AU - de Hingh, Ignace H.

PY - 2016/12

Y1 - 2016/12

N2 - With the introduction of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), long-term survival can be achieved in selected patients with colorectal peritoneal metastases (PM). Patient selection and outcome may be improved significantly with a tool that adequately predicts survival in these patients. This study was designed to validate the peritoneal surface disease severity score (PSDSS) in patients with colorectal PM treated with CRS?+?HIPEC. If performance of the PSDSS was suboptimal (c?

AB - With the introduction of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), long-term survival can be achieved in selected patients with colorectal peritoneal metastases (PM). Patient selection and outcome may be improved significantly with a tool that adequately predicts survival in these patients. This study was designed to validate the peritoneal surface disease severity score (PSDSS) in patients with colorectal PM treated with CRS?+?HIPEC. If performance of the PSDSS was suboptimal (c?

U2 - 10.1245/s10434-016-5211-6

DO - 10.1245/s10434-016-5211-6

M3 - Article

C2 - 27027308

SN - 1068-9265

VL - 23

SP - 4214

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JO - Annals of Surgical Oncology

JF - Annals of Surgical Oncology

IS - 13

ER -

Development of a Prognostic Nomogram for Patients with Peritoneally Metastasized Colorectal Cancer Treated with Cytoreductive Surgery and HIPEC

Abstract

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