Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity

N.R. Franco*, M.C. Massi, F. Ieva, A. Manzoni, A.M. Paganoni, P. Zunino, L. Veldeman, P. Ost, V. Fonteyne, C.J. Talbot, T. Rattay, A. Webb, K. Johnson, M. Lambrecht, K. Haustermans, G. De Meerleer, D. de Ruysscher, B. Vanneste, E. Van Limbergen, A. ChoudhuryR.M. Elliot, E. Sperk, M.R. Veldwijk, C. Herskind, B. Auvzzi, B.N. Chiorda, R. Valdagni, D. Azria, M.P. Farcy-Jacquet, M. Brengues, B.S. Rosenstein, R.G. Stock, A. Vega, M.E. Aguado-Barrera, P. Sosa-Fajardo, A.M. Dunning, L. Fachal, S.L. Kerns, D. Payne, J. Chang-Claude, P. Seibold, C.M.L. West, T. Rancati, Consortium REQUITE, REQUITE consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Web of Science)
Original languageEnglish
Pages (from-to)241-248
Number of pages8
JournalRadiotherapy and Oncology
Volume159
DOIs
Publication statusPublished - 1 Jun 2021

Keywords

  • Prostate cancer
  • Radiotherapy
  • Late toxicity
  • Genetic risk factors
  • SNPs
  • Epistasis
  • EPISTASIS
  • REQUITE

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