Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis

Kirsten van de Groep, Martine P. Bos, Paul H. M. Savelkoul, Anna Rubenjan, Christel Gazenbeek, Willem J. G. Melchers, Tom van der Poll, Nicole P. Juffermans, David S. Y. Ong, Marc J. M. Bonten, Olaf L. Cremer, MARS Consortium

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1333-1344
Number of pages12
JournalEuropean Journal of Clinical Microbiology & Infectious Diseases
Volume37
Issue number7
DOIs
Publication statusPublished - 1 Jul 2018

Keywords

  • Bloodstream infection
  • Sepsis
  • Intensive care
  • Diagnosis
  • Multiplex real-time PCR
  • INTENSIVE-CARE-UNIT
  • RESISTANT STAPHYLOCOCCUS-AUREUS
  • STREAM INFECTIONS
  • ENTEROCOCCUS-FAECALIS
  • SEPTIC SHOCK
  • DIAGNOSIS
  • ASSAY
  • MORTALITY
  • DNA
  • BACTEREMIA

Cite this

van de Groep, K., Bos, M. P., Savelkoul, P. H. M., Rubenjan, A., Gazenbeek, C., Melchers, W. J. G., van der Poll, T., Juffermans, N. P., Ong, D. S. Y., Bonten, M. J. M., Cremer, O. L., & MARS Consortium (2018). Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis. European Journal of Clinical Microbiology & Infectious Diseases, 37(7), 1333-1344. https://doi.org/10.1007/s10096-018-3255-1