Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

Qing Cheng; Erik Roelofs; Bram L. T. Ramaekers; Danielle Eekers; Johan van Soest; Tim Lustberg; Tim Hendriks; Frank Hoebers; Hans Paul van der Laan; Erik W. Korevaar; Andre Dekker; Johannes A. Langendijk; Philippe Lambin

doi:10.1016/j.radonc.2015.12.029

Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

Qing Cheng
, Erik Roelofs
, Bram L. T. Ramaekers
, Danielle Eekers
, Johan van Soest
, Tim Lustberg
, Tim Hendriks
, Frank Hoebers
, Hans Paul van der Laan
, Erik W. Korevaar
, Andre Dekker
, Johannes A. Langendijk
, Philippe Lambin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets.

Original language	English
Pages (from-to)	281-285
Number of pages	5
Journal	Radiotherapy and Oncology
Volume	118
Issue number	2
DOIs	https://doi.org/10.1016/j.radonc.2015.12.029
Publication status	Published - Feb 2016

Keywords

Proton therapy
Decision support system
Quantitative comparison
Mean dose extraction
Toxicity prediction
Cost-effectiveness estimation

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10.1016/j.radonc.2015.12.029Licence: CC BY-NC-ND

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Cheng, Q., Roelofs, E., Ramaekers, B. L. T., Eekers, D., van Soest, J., Lustberg, T., Hendriks, T., Hoebers, F., van der Laan, H. P., Korevaar, E. W., Dekker, A., Langendijk, J. A., & Lambin, P. (2016). Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness. Radiotherapy and Oncology, 118(2), 281-285. https://doi.org/10.1016/j.radonc.2015.12.029

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title = "Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness",

abstract = "To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets. ",

keywords = "Proton therapy, Decision support system, Quantitative comparison, Mean dose extraction, Toxicity prediction, Cost-effectiveness estimation",

author = "Qing Cheng and Erik Roelofs and Ramaekers, \{Bram L. T.\} and Danielle Eekers and \{van Soest\}, Johan and Tim Lustberg and Tim Hendriks and Frank Hoebers and \{van der Laan\}, \{Hans Paul\} and Korevaar, \{Erik W.\} and Andre Dekker and Langendijk, \{Johannes A.\} and Philippe Lambin",

year = "2016",

month = feb,

doi = "10.1016/j.radonc.2015.12.029",

language = "English",

volume = "118",

pages = "281--285",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

Cheng, Q, Roelofs, E , Ramaekers, BLT , Eekers, D , van Soest, J, Lustberg, T, Hendriks, T, Hoebers, F, van der Laan, HP, Korevaar, EW, Dekker, A, Langendijk, JA & Lambin, P 2016, 'Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness', Radiotherapy and Oncology, vol. 118, no. 2, pp. 281-285. https://doi.org/10.1016/j.radonc.2015.12.029

Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness. / Cheng, Qing; Roelofs, Erik ; Ramaekers, Bram L. T. et al.
In: Radiotherapy and Oncology, Vol. 118, No. 2, 02.2016, p. 281-285.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

AU - Cheng, Qing

AU - Roelofs, Erik

AU - Ramaekers, Bram L. T.

AU - Eekers, Danielle

AU - van Soest, Johan

AU - Lustberg, Tim

AU - Hendriks, Tim

AU - Hoebers, Frank

AU - van der Laan, Hans Paul

AU - Korevaar, Erik W.

AU - Dekker, Andre

AU - Langendijk, Johannes A.

AU - Lambin, Philippe

PY - 2016/2

Y1 - 2016/2

N2 - To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets.

AB - To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets.

KW - Proton therapy

KW - Decision support system

KW - Quantitative comparison

KW - Mean dose extraction

KW - Toxicity prediction

KW - Cost-effectiveness estimation

U2 - 10.1016/j.radonc.2015.12.029

DO - 10.1016/j.radonc.2015.12.029

M3 - Article

C2 - 26924342

SN - 0167-8140

VL - 118

SP - 281

EP - 285

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - 2

ER -

Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

Abstract

Keywords

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